Universitätshautklinik
Haus 14
Leipziger Str. 44
39120 Magdeburg
Direktor: Prof. Dr. med. T. Tüting
Advanced deep learning for skin histoglyphics at cellular level
In: Bildverarbeitung für die Medizin 2024 - Wiesbaden : Springer Fachmedien Wiesbaden ; Maier, Andreas *1980-*, S. 66-71
Low skeletal muscle mass predicts melanoma-specific survival in melanoma patients treated with adjuvant immune checkpoint blockade
In: Journal of cancer research and clinical oncology - Berlin : Springer, Bd. 150 (2024), Heft 5, Artikel 275, insges. 9 S.
Effectiveness, safety and utilization of cobimetinib and vemurafenib in patients with BRAF V600 mutant melanoma with and without cerebral metastasis under real-world conditions in Germany - the non-interventional study coveNIS
In: Melanoma research - Hagerstown, Md. : Lippincott Williams & Wilkins, Bd. 34 (2024), Heft 1, S. 44-53
A replicating LCMV-based vaccine for the treatment of solid tumors
In: Molecular therapy - Amsterdam : Elsevier, Bd. 32 (2024), Heft 2, S. 426-439
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation
In: Nature cancer - London : Nature Research, Bd. 5 (2024), Heft 3, S. 433-447, insges. 28 S.
Die Bedeutung von Sarkopenie für die immunvermittelte Toxizität bei Patienten mit malignem Melanom unter einer Immuncheckpoint-Inhibition - Sarcopenia and immune-related toxicity in patients with malignant melanoma undergoing immune checkpoint inhibition
In: Die Dermatologie - [Berlin] : Springer Medizin Verlag GmbH, Bd. 75 (2024), Heft 10, S. 798-803
Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice
In: Cancer gene therapy - New York, NY : Nature Publ. Group, Bd. 31 (2024), Heft 6, S. 884-893
Comprehensive analysis of body composition features in melanoma patients treated with tyrosine kinase inhibitors
In: Journal der Deutschen Dermatologischen Gesellschaft / Deutsche Dermatologische Gesellschaft - Berlin : Wiley-Blackwell, Bd. 22 (2024), Heft 6, S. 783-791
Malignes Melanom
In: DGIM Innere Medizin , Living Reference Work, continuously updated edition - Berlin, Heidelberg : Springer ; Lehnert, Hendrik *1954-* . - 2023, S. 1-8
CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours
In: Nature
Subcutaneous fat abundance and density are associated with an enhanced response to immunotherapy in metastatic melanoma - a retrospective cohort study
In: Academic radiology - Philadelphia, PA [u.a.] : Elsevier, Bd. 30 (2023), Heft Supplement 1, S. S257-S267
Acantholytic squamous cell carcinoma in a patient with junctional epidermolysis bullosa - Akantholytisches Plattenepithelkarzinom bei einer Patientin mit junktionaler Epidermolysis bullosa
In: Journal der Deutschen Dermatologischen Gesellschaft / Deutsche Dermatologische Gesellschaft - Berlin : Wiley-Blackwell, Bd. 21 (2023), Heft 7, S. 798-801
N-glycosylation regulates intrinsic IFN-γ resistance in colorectal cancer - implications for immunotherapy
In: Gastroenterology - Stanford, Calif. : HighWire Press, Bd. 164 (2023), Heft 3, S. 392-406.e5
CLL-derived extracellular vesicles impair T-cell activation and foster T-cell exhaustion via multiple immunological checkpoints
In: Cells - Basel : MDPI, Bd. 11 (2022), Heft 14, Artikel 2176, insges. 20 S.
Kognitive Funktionsstörungen unter Systemtherapie bei metastasiertem Melanom - Immunological mechanisms of cognitive dysfunction under systemic therapy in metastatic melanoma
In: Die Dermatologie - [Berlin]: Springer Medizin Verlag GmbH, Bd. 73 (2022), 12, S. 937-942
Prognosis of patients with primary melanoma stage I and II according to American Joint Committee on Cancer version 8 validated in two independent cohorts - implications for adjuvant treatment
In: Journal of clinical oncology - Alexandria, Va. : American Society of Clinical Oncology, Bd. 40 (2022), Heft 32, S. 3741-3749, insges. 13 S.
Neutrophils activated by membrane attack complexes increase the permeability of melanoma blood vessels
In: Proceedings of the National Academy of Sciences of the United States of America/ National Academy of Sciences - Washington, DC: National Acad. of Sciences, Bd. 119 (2022), Heft 33, S. 1-12, Artikel e2122716119, insges. 12 S.
Tumor cell intrinsic Toll-like receptor 4 signaling promotes melanoma progression and metastatic dissemination
In: International journal of cancer - Bognor Regis: Wiley-Liss, 1966, Bd. 150 (2022), 1, S. 142-151
XIAP promotes melanoma growth by inducing tumour neutrophil infiltration
In: EMBO reports/ European Molecular Biology Organization - Heidelberg: EMBO Press, 2000, Bd. 23 (2022), 6, insges. 15 S.
CRISPitope - a generic platform to model target antigens for adoptive T cell transfer therapy in mouse tumor models
In: STAR Protocols - Cambridge, MA: Cell Press, 2020, Bd. 3 (2022), 1, insges. 28 S.
Persistent facial swelling - Persistierende Schwellung des Gesichts
In: Journal der Deutschen Dermatologischen Gesellschaft/ Deutsche Dermatologische Gesellschaft - Berlin: Wiley-Blackwell, Bd. 20 (2022), 7, S. 1033-1036
Multi-objective evolutionary game theory - a case study in cancer therapy
In: Proceedings of the Artificial Life Conference 2022, ALIFE ; Holler, Silvia, Artikel isal_a_00498,20, insges. 3 S. [Konferenz: Conference on Artificial Life, ALIFE 2022, online, July 18-22, 2022]
Unterschätzte Technik - Die kombinierte Oberflächenhyperthermie/hypofraktionierte Radiotherapie (HRT) für lokal rezidivierte Mammakarzinome, Plattenepithelkarzinome sowie Basalzellkarzinome der Haut
In: Ärzteblatt Sachsen-Anhalt - offizielles Mitteilungsblatt der Ärztekammer Sachsen-Anhalt - Magdeburg: Ärztekammer Sachsen-Anhalt, Bd. 33 (2022), 11, S. 25-28
Photokarzinogenese - Molekulare Mechanismen und praktische Relevanz
In: Der Hautarzt: Organ der Deutschen Dermatologischen Gesellschaft - Berlin: Springer, Bd. 72 (2021), 1, S. 6-13
E3 ubiquitin ligase HECTD2 mediates melanoma progression and immune evasion
In: Oncogene - London: Springer Nature, 1997, Bd. 40 (2021), 37, S. 5567-5578
The myeloid cell type I IFN system promotes antitumor immunity over pro-tumoral inflammation in cancer T-cell therapy
In: Clinical & Translational Immunology - Hoboken, NJ: Wiley, 2012, Bd. 10 (2021), insges. 14 S.
Prognosis of patients with stage III melanoma according to American Joint Committee on Cancer version 8 - a reassessment on the basis of 3 independent stage III melanoma cohorts
In: Journal of clinical oncology - Alexandria, Va.: American Society of Clinical Oncology, 1983, Bd. 38 (2020), 22, S. 2543-2551, insges. 9 S.
Comprehensive visualization of longitudinal patient data for the dermatological oncological tumor board
In: EuroVis 2020 - Eurographics Association ; Kerren, Andreas, S. 169-173
Activated Hgf-Met signaling cooperates with oncogenic BRAF to drive primary cutaneous melanomas and angiotropic lung metastases in mice
In: The journal of investigative dermatology - Amsterdam: Elsevier, Bd. 140 (2020), 7, S. 1410-1417.e2
The aryl hydrocarbon receptor promotes inflammation-induced dedifferentiation and systemic metastatic spread of melanoma cells
In: International journal of cancer - Bognor Regis: Wiley-Liss, 1966, Bd. 147 (2020), 10, S. 2902-2913
Cannabinoid receptor 2 modulates maturation of dendritic cells and their capacity to induce hapten-induced contact hypersensitivity
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 2, Art.-Nr, 475, insgesamt 12 Seiten
Successful treatment of non-uremic calciphylaxis with bisphosphonate. Clinical letter
In: Journal der Deutschen Dermatologischen Gesellschaft/ Deutsche Dermatologische Gesellschaft - Berlin: Wiley-Blackwell, Bd. 18 (2020), 12, S. 1498-1500
Combined immunotherapy with nivolumab and ipilimumab with and without local therapy in patients with melanoma brain metastasis - a DeCOG* study in 380 patients
In: Journal for ImmunoTherapy of Cancer: official journal of the Society for Immunotherapy of Cancer (SITC) - London: BioMed Central, 2013, Vol. 8.2020,1, Artikel-Nummer e000333, 11 Seiten[Gesehen am 06.10.2020]
Adoptive T cell therapy targeting different gene products reveals diverse and context-dependent immune evasion in melanoma
In: Immunity - [Cambridge, Mass.]: Cell Press, 1994, Bd. 53.2020, 3, S. 564-580.e9
Age as key factor for pattern, timing and extent of distant metastasis in patients with cutaneous melanoma - a study of the German Central Malignant Melanoma Registry
In: Journal of the American Academy of Dermatology/ American Academy of Dermatology - Amsterdam [u.a.]: Elsevier, 1979, Bd. 80 (2019), 5, S. 1299-1307.e7
Pancreatic panniculitis with polyarthritis (PPP syndrome) - clinical letter
In: Journal der Deutschen Dermatologischen Gesellschaft/ Deutsche Dermatologische Gesellschaft - Berlin: Wiley-Blackwell, Bd. 17 (2019), 5, S. 546-547
Safety and efficacy of topically applied selected Cutibacterium acnes strains over five weeks in patients with acne vulgaris - an open-label, pilot study
In: Acta dermato-venereologica - Uppsala: Acta Dermato-Venereologica, 1946, Bd. 99 (2019), 13, S. 1253-1257
Role of the aryl hydrocarbon receptor in environmentally induced skin aging and skin carcinogenesis
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd.20.2019, 23, Art.-Nr. 6005, insges. 21 S.
Personalisierte Medizin
In: Der Hautarzt: Organ der Deutschen Dermatologischen Gesellschaft - Berlin: Springer, Bd. 70.2019, 1, S. 4
Cutaneous and pulmonary botryomycosis
In: The lancet
Live or let die - T cell survival in cancer immunotherapy
In: Immunity - [Cambridge, Mass.]: Cell Press, Bd. 50.2019, 2, S. 280-282
Tissue-resident memory CD8+ T cells promote melanoma-immune equilibrium in skin
In: Nature
Detection of a multilineage mosaic NRAS mutation c.181C>A (p.Gln61Lys) in an individual with a complex congenital nevus syndrome. Letter to the editor
In: Pigment cell & melanoma research - Oxford [u.a.]: Wiley-Blackwell, Bd. 32.2019, 3, S. 470-473
Direct targeting of Gαq and Gα11 oncoproteins in cancer cells
In: Science signaling - Washington, DC [u.a.]: Assoc., Bd. 12.2019, 573, eaau5948, insges. 14 S.
Acral lentiginous melanoma - a skin cancer with unfavourable prognostic features : a study of the German Central Malignant Melanoma Registry (CMMR) in 2050 patients
In: British journal of dermatology - Oxford : Oxford University Press, Bd. 178 (2018), Heft 2, S. 443-451
RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas
In: Oncogene - London: Springer Nature, 1997, Bd. 37.2018, 47, S. 6136-6151, insges. 15 S.[Gesehen am 13.11.2019]
Widespread spontaneous hyperproliferation, melanosis and melanoma in Hgf-Cdk4R24C mice. Letter to the editor
In: Melanoma research - Hagerstown, Md. : Lippincott Williams & Wilkins, Bd. 28.2018, 1, S. 76-78
Von Hauteffloreszenzen zum pulmorenalen Syndrom - Eine überraschende Ursache für eine systemische Vaskulitis
In: Der Nephrologe: Zeitschrift für Nephrologie und Hypertensiologie - Berlin: Springer, Bd. 13.2018, 6, S. 411-415
Restoration of endogenous retrovirus infectivity impacts mouse cancer models
In: Cancer immunology research: illuminating the interplay of cancer and the immune system - Philadelphia, Pa: AACR, Bd. 6.2018, 11, S. 1292-1300
The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma
In: Journal of experimental medicine - New York, NY : Rockefeller Univ. Press, Bd. 214 (2017), Heft 2, S. 339-358
Basophils promote tumor rejection via chemotaxis and infiltration of CD8+ T cells
In: Cancer research - Philadelphia, Pa. : AACR, Bd. 77 (2017), Heft 2, S. 291-302
Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. Letter
In: Nature
Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma
In: Genes & development - Stanford, Calif: HighWire Press, Bd. 31 (2017), 1, S. 18-33
RIG-I resists hypoxia-induced immunosuppression and dedifferentiation
In: Cancer immunology research: illuminating the interplay of cancer and the immune system - Philadelphia, Pa.: AACR, 2013, Bd. 5.2017, 6, S. 455-467
MAPK signaling and inflammation link melanoma phenotype switching to induction of CD73 during immunotherapy
In: Cancer research - Philadelphia, Pa. : AACR, Bd. 77 (2017), Heft 17, S. 4697-4709, insges. 13 S.
Deletion of ADAM-9 in HGF/CDK4 mice impairs melanoma development and metastasis
In: Oncogene - London: Springer Nature, Bd. 36 (2017), 35, S. 5058-5067
Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression
In: OncoImmunology - Abingdon: Taylor & Franics, Bd. 6 (2017), 6
Reactive neutrophil responses dependent on the receptor tyrosine kinase c-MET limit cancer immunotherapy
In: Immunity - [Cambridge, Mass.]: Cell Press, Bd. 47 (2017), 4, S. 789-802
A stochastic model for immunotherapy of cancer
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 6.2016, Art.-Nr. 24169, insges. 10 S.
Overexpression of hepatocyte growth factor and an oncogenic CDK4 variant in mice alters corneal stroma morphology but does not lead to spontaneous ocular melanoma
In: Melanoma Research, 2016, S. 89-91, ISSN 0960-8931, 10.1097/CMR.0000000000000206
Directed Dedifferentiation Using Partial Reprogramming Induces Invasive Phenotype in Melanoma Cells
In: STEM CELLS, 2016, S. 832-846, ISSN 10665099, 10.1002/stem.2284
Die tumorimmunologische Revolution in der Behandlung des fortgeschrittenen Melanoms. Editorial
In: Journal der Deutschen Dermatologischen Gesellschaft : JDDG. - Berlin : Wiley-Blackwell, Bd. 14.2016, 7, S. 655-656
How neutrophils promote metastasis - Neutrophils may be cellular targets for cancer therapy
In: Science. - Washington, DC [u.a.] : American Association for the Advancement of Science, Bd. 352.2016, 6282, S. 145-146
Inflammation-induced plasticity in melanoma therapy and metastasis
In: Trends in immunology. - Amsterdam [u.a.] : Elsevier Science, Bd. 37.2016, 6, S. 364-374
Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes
In: Nature Communications - [London]: Nature Publishing Group UK, 2010, Bd. 7.2016, Art.-Nr. 13515, insges. 17 S.
A Preclinical Model of Malignant Peripheral Nerve Sheath Tumor-like Melanoma Is Characterized by Infiltrating Mast Cells
In: Cancer Research, 2016, S. 251-263, ISSN 0008-5472, 10.1158/0008-5472.CAN-15-1090
MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment
In: Nature Communications, Vol. 6, 2015, 10.1038/ncomms9755
Self-Antigen Presentation by Keratinocytes in the Inflamed Adult Skin Modulates T-Cell Auto-Reactivity
In: Journal of Investigative Dermatology, Vol. 135, 2015, Issue 8, S. 1996-2004, 10.1038/jid.2015.130
Differential role of cannabinoids in the pathogenesis of skin cancer
In: Life Sciences, Vol. 138, 2015, S. 35-40, 10.1016/j.lfs.2015.04.003
Dickkopf-3 contributes to the regulation of anti-tumor immune responses by mesenchymal stem cells
In: Frontiers in Immunology, Vol. 6, 2015, Issue DEC, 10.3389/fimmu.2015.00645
Phorbol ester-induced neutrophilic inflammatory responses selectively promote metastatic spread of melanoma in a TLR4-dependent manner
In: OncoImmunology, 2015, S. e1078964, ISSN 2162-402X, 10.1080/2162402X.2015.1078964
β-arrestin 2 inhibits proinflammatory chemokine production and attenuates contact allergic inflammation in the skin
In: Journal of Investigative Dermatology, Vol. 134, 2014, Issue 8, S. 2131-2137, 10.1038/jid.2014.117
Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy
In: Nature medicine, Vol. 20, 2014, Issue 11, S. 1301-1309, 10.1038/nm.3708
A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation
In: Chemistry and Biology, Vol. 21, 2014, Issue 7, S. 890-902, 10.1016/j.chembiol.2014.06.003
Cannabinoid 1 receptors in keratinocytes attenuate fluorescein isothiocyanate-induced mouse atopic-like dermatitis
In: Experimental Dermatology, Vol. 23, 2014, Issue 6, S. 401-406, 10.1111/exd.12414
Immune cell-poor melanomas benefit from PD-1 blockade after targeted type I IFN activation
In: Cancer Discovery, Vol. 4, 2014, Issue 6, S. 674-687, 10.1158/2159-8290.CD-13-0458
Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma
In: Nature, Vol. 507, 2014, Issue 7490, S. 109-113, 10.1038/nature13111
Anti-inflammatory activity of topical THC in DNFB-mediated mouse allergic contact dermatitis independent of CB1 and CB2 receptors
In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 68, 2013, Issue 8, S. 994-1000, 10.1111/all.12183
T cell immunotherapy for melanoma from bedside to bench to barn and back: How conceptual advances in experimental mouse models can be translated into clinical benefit for patients
In: Pigment Cell and Melanoma Research, Vol. 26, 2013, Issue 4, S. 441-456, 10.1111/pcmr.12111
Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation
In: Journal of Immunology, Vol. 190, 2013, Issue 10, S. 4929-4936, 10.4049/jimmunol.1201777
Oxidative damage of dna confers resistance to cytosolic nuclease trex1 degradation and potentiates STING-dependent immune sensing
In: Immunity, Vol. 39, 2013, Issue 3, S. 482-495, 10.1016/j.immuni.2013.08.004
Plasticity of tumour and immune cells: A source of heterogeneity and a cause for therapy resistance?
In: Nature Reviews Cancer, Vol. 13, 2013, Issue 5, S. 365-376, 10.1038/nrc3498
Biolistic DNA vaccination against melanoma
In: Methods in Molecular Biology, Vol. 940, 2013, S. 317-337, 10.1007/978-1-62703-110-3_24
Nitrosative stress: A hallmark of the junctional inflammation in cutaneous lupus erythematosus
In: Clinical and Experimental Dermatology, Vol. 38, 2013, Issue 1, S. 96-97, 10.1111/j.1365-2230.2012.04472.x
Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation
In: Nature, Vol. 490, 2012, Issue 7420, S. 412-416, 10.1038/nature11538
Efficacy of low-dose methotrexate in the treatment of dermatomyositis skin lesions
In: Clinical and Experimental Dermatology, Vol. 37, 2012, Issue 2, S. 139-142, 10.1111/j.1365-2230.2011.04188.x
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease
In: Nature, Vol. 480, 2011, Issue 7378, S. 543-546, 10.1038/nature10671
Enhanced CCR5+/CCR3+ T helper cell ratio in patients with active cutaneous lupus erythematosus
In: Lupus, Vol. 20, 2011, Issue 12, S. 1300-1304, 10.1177/0961203311409267
Immunogenic cell death of human ovarian cancer cells induced by cytosolic poly(I:C) leads to myeloid cell maturation and activates NK cells
In: European Journal of Immunology, Vol. 41, 2011, Issue 10, S. 3028-3039, 10.1002/eji.201141555
Neonatal UVB exposure accelerates melanoma growth and enhances distant metastases in Hgf-Cdk4 R24C C57BL/6 mice
In: International Journal of Cancer, Vol. 129, 2011, Issue 2, S. 285-294, 10.1002/ijc.25913
Enhanced skin expression of melanoma differentiation-associated gene 5 (MDA5) in dermatomyositis and related autoimmune diseases
In: Journal of the American Academy of Dermatology, Vol. 64, 2011, Issue 5, S. 988-989, 10.1016/j.jaad.2010.08.004
Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFNλ) in cutaneous lupus erythematosus
In: Journal of Investigative Dermatology, Vol. 131, 2011, Issue 1, S. 133-140, 10.1038/jid.2010.244
Screening of human tumor antigens for CD4+ T cell epitopes by combination of HLA-transgenic mice, recombinant adenovirus and antigen peptide libraries
In: PLoS ONE, Vol. 5, 2010, Issue 11, 10.1371/journal.pone.0014137
Of swords and ploughshares: Immunosurveillance and inflammation in melanoma
In: Pigment Cell and Melanoma Research, Vol. 23, 2010, Issue 6, S. 727-728, 10.1111/j.1755-148X.2010.00754.x
Autochthonous primary and metastatic melanomas in Hgf-Cdk4R24C mice evade T-cell-mediated immune surveillance
In: Pigment Cell and Melanoma Research, Vol. 23, 2010, Issue 5, S. 649-660, 10.1111/j.1755-148X.2010.00744.x
Pathogenesis of cutaneous lupus erythematosus: Common and different features in distinct subsets
In: Lupus, Vol. 19, 2010, Issue 9, S. 1020-1028, 10.1177/0961203310370046
Bioluminescence imaging allows measuring CD8 T cell function in the liver
In: Hepatology, Vol. 51, 2010, Issue 4, S. 1430-1437, 10.1002/hep.23575
Multicentre study on standardisation of melanoma cell culture - An initiative of the German Melanoma Research Network
In: Pigment Cell and Melanoma Research, Vol. 23, 2010, Issue 2, S. 296-298, 10.1111/j.1755-148X.2010.00684.x
Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, 2010, Issue 1, S. 216-221, 10.1073/pnas.0909541107
Protective role of palmitoylethanolamide in contact allergic dermatitis
In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 65, 2010, Issue 6, S. 698-711, 10.1111/j.1398-9995.2009.02254.x
Identification of a 17β-hydroxysteroid dehydrogenase type 12 pseudogene as the source of a highly restricted BALB/c Meth A tumor rejection peptide
In: Cancer Immunology, Immunotherapy, Vol. 59, 2010, Issue 1, S. 113-124, 10.1007/s00262-009-0730-7
Autochthonous liver tumors induce systemic T cell tolerance associated with T cell receptor down-modulation
In: Hepatology, Vol. 49, 2009, Issue 2, S. 471-481, 10.1002/hep.22652
Interferon-α differentially affects homeostasis of human plasmacytoid and myeloid dendritic cells
In: Journal of Interferon and Cytokine Research, Vol. 29, 2009, Issue 3, S. 145-159, 10.1089/jir.2008.0011
Type I interferon-associated cytotoxic inflammation in cutaneous lupus erythematosus
In: Archives of Dermatological Research, Vol. 301, 2009, Issue 1, S. 83-86, 10.1007/s00403-008-0892-8
Multiple skin cancers in a patient treated with hydroxyurea [Multiple kutane Neoplasien nach Therapie mit Hydroxyurea]
In: Hautarzt, Vol. 60, 2009, Issue 8, S. 651-654, 10.1007/s00105-008-1673-1
Complete regression of advanced primary and metastatic mouse melanomas following combination chemoimmunotherapy
In: Cancer Research, Vol. 69, 2009, Issue 15, S. 6265-6274, 10.1158/0008-5472.CAN-09-0579
Targeted Activation of Innate Immunity for Therapeutic Induction of Autophagy and Apoptosis in Melanoma Cells
In: Cancer Cell, Vol. 16, 2009, Issue 2, S. 103-114, 10.1016/j.ccr.2009.07.004
New ways in melanoma therapy [Neue wege in der melanomtherapie]
In: JDDG - Journal of the German Society of Dermatology, Vol. 6, 2008, Issue 10, S. 815-816, 10.1111/j.1610-0387.2008.06879.x
An IFN-associated cytotoxic cellular immune response against viral, self-, or tumor antigens is a common pathogenetic feature in "interface dermatitis"
In: Journal of Investigative Dermatology, Vol. 128, 2008, Issue 10, S. 2392-2402, 10.1038/jid.2008.96
The R620W polymorphism in PTPN22 confers general susceptibility for the development of alopecia areata
In: British Journal of Dermatology, Vol. 158, 2008, Issue 2, S. 389-391, 10.1111/j.1365-2133.2007.08312.x
Gene expression profiling of lichen planus reflects CXCL9+-mediated inflammation and distinguishes this disease from atopic dermatitis and psoriasis
In: Journal of Investigative Dermatology, Vol. 128, 2008, Issue 1, S. 67-78, 10.1038/sj.jid.5700945
Sézary syndrome is a unique cutaneous T-cell lymphoma as identified by an expanded gene signature including diagnostic marker molecules CDO1 and DNM3
In: Leukemia, Vol. 22, 2008, Issue 2, S. 393-399, 10.1038/sj.leu.2405044
Toll-like receptor-agonists in the treatment of skin cancer: History, current developments and future prospects
In: Handbook of Experimental Pharmacology, Vol. 183, 2008, S. 201-220, 10.1007/978-3-540-72167-3-10
Transcriptional profiling identifies an interferon-associated host immune response in invasive squamous cell carcinoma of the skin
In: International Journal of Cancer, Vol. 123, 2008, Issue 11, S. 2605-2615, 10.1002/ijc.23799
5′-triphosphate-siRNA: Turning gene silencing and Rig-I activation against melanoma
In: Nature Medicine, Vol. 14, 2008, Issue 11, S. 1256-1263, 10.1038/nm.1887
Preoperative 18F-FDG-PET/CT imaging and sentinel node biopsy in the detection of regional lymph node metastases in malignant melanoma
In: Melanoma Research, Vol. 18, 2008, Issue 5, S. 346-352, 10.1097/CMR.0b013e32830b363b
Subacute cutaneous lupus erythematosus in a leuprorelin-treated patient with prostate carcinoma
In: British Journal of Dermatology, Vol. 159, 2008, Issue 1, S. 231-233, 10.1111/j.1365-2133.2008.08587.x
Successful treatment of recalcitrant malar rash in a patient with cutaneous lupus erythematosus with efalizumab
In: Clinical and Experimental Dermatology, Vol. 33, 2008, Issue 3, S. 347-348, 10.1111/j.1365-2230.2007.02648.x
CXCR3 <-> ligand-mediated skin inflammation in cutaneous lichenoid graft-versus-host disease
In: Journal of the American Academy of Dermatology, Vol. 58, 2008, Issue 3, S. 437-442, 10.1016/j.jaad.2007.10.647
Preclinical development of melanoma vaccines with toll-like receptor ligands in a novel genetic mouse model
In: Arzneimittel-Forschung/Drug Research, Vol. 57, 2007, Issue 1, S. 67
Comparative evaluation of CD8+CTL responses following gene gun immunization targeting the skin with intracutaneous injection of antigen-transduced dendritic cells
In: European Journal of Cell Biology, Vol. 86, 2007, Issue 11-12, S. 817-826, 10.1016/j.ejcb.2006.07.002
Indoleamine 2,3-dioxygenase (IDO): The antagonist of type I interferon-driven skin inflammation?
In: American Journal of Pathology, Vol. 171, 2007, Issue 6, S. 1936-1943, 10.2353/ajpath.2007.070281
Loss-of-function mutations in the filaggrin gene and alopecia areata: Strong risk factor for a severe course of disease in patients comorbid for atopic disease
In: Journal of Investigative Dermatology, Vol. 127, 2007, Issue 11, S. 2539-2543, 10.1038/sj.jid.5700915
The neoplastic T cells' culture in cutaneous T cell lymphomas - Never ending challenge [Hodowla nowotworowych komórek T w chÅ¿oniakach pierwotnie skórnych z komórek T - Nieustaja̧ce wyzwanie]
In: Przeglad Dermatologiczny, Vol. 94, 2007, Issue 4, S. 495-499
Application study Bepanthol Body Lotion Plus for atopic skin [Anwendungsbeobachtung Bepanthol Körperlotion Plus bei atopischer Haut]
In: Kosmetische Medizin, Vol. 28, 2007, Issue 4, S. 182-185
The expression pattern of interferon-inducible proteins reflects the characteristic histological distribution of infiltrating immune cells in different cutaneous lupus erythematosus subsets
In: British Journal of Dermatology, Vol. 157, 2007, Issue 4, S. 752-757, 10.1111/j.1365-2133.2007.08137.x
Attenuation of allergic contact dermatitis through the endocannabinoid system
In: Science, Vol. 316, 2007, Issue 5830, S. 1494-1497, 10.1126/science.1142265
Successful treatment of bullous congenital ichthyosiform erythroderma with erythromycin [2]
In: Dermatology, Vol. 215, 2007, Issue 1, S. 81-83, 10.1159/000102043
Identification of type I interferon-associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches
In: Experimental Dermatology, Vol. 16, 2007, Issue 5, S. 454-463, 10.1111/j.1600-0625.2007.00556.x
IP10/CXCL10 - CXCR3 interaction: A potential self-recruiting mechanism for cytotoxic lymphocytes in lichen sclerosus et atrophicus
In: Acta Dermato-Venereologica, Vol. 87, 2007, Issue 2, S. 112-117, 10.2340/00015555-0194
CXCR3-mediated recruitment of cytotoxic lymphocytes in lupus erythematosus profundus
In: Journal of the American Academy of Dermatology, Vol. 56, 2007, Issue 4, S. 648-650, 10.1016/j.jaad.2006.08.014
Additional Her 2/neu gene copies in patients with Sézary syndrome
In: Leukemia Research, Vol. 30, 2006, Issue 6, S. 755-760, 10.1016/j.leukres.2005.10.012
Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO
In: European Journal of Immunology, Vol. 36, 2006, Issue 1, S. 12-20, 10.1002/eji.200535602
Evaluation of genetic melanoma vaccines in cdk4-mutant mice provides evidence for immunological tolerance against autochthonous melanomas in the skin
In: International Journal of Cancer, Vol. 118, 2006, Issue 2, S. 373-380, 10.1002/ijc.21349
Proteasome-inhibited dendritic cells demonstrate improved presentation of exogenous synthetic and natural HLA-class I peptide epitopes
In: Journal of Immunological Methods, Vol. 308, 2006, Issue 1-2, S. 77-89, 10.1016/j.jim.2005.09.021
Diagnostic performance of whole body dual modality 18F-FDG PET/CT imaging for N- and M-staging of malignant melanoma: Experience with 250 consecutive patients
In: Journal of Clinical Oncology, Vol. 24, 2006, Issue 7, S. 1178-1187, 10.1200/JCO.2005.03.5634
Effective induction of anti-melanoma immunity following genetic vaccination with synthetic mRNA coding for the fusion protein EGFP.TRP2
In: Cancer Immunology, Immunotherapy, Vol. 55, 2006, Issue 3, S. 246-253, 10.1007/s00262-005-0042-5
Comparison of recombinant adenovirus and synthetic peptide for DC-based melanoma vaccination
In: Cancer Gene Therapy, Vol. 13, 2006, Issue 3, S. 318-325, 10.1038/sj.cgt.7700894
Therapeutic efficacy of antigen-specific vaccination and toll-like receptor stimulation against established transplanted and autochthonous melanoma in mice
In: Cancer Research, Vol. 66, 2006, Issue 10, S. 5427-5435, 10.1158/0008-5472.CAN-06-0399
Type I interferon-associated skin recruitment of CXCR3+ lymphocytes in dermatomyositis
In: Clinical and Experimental Dermatology, Vol. 31, 2006, Issue 4, S. 576-582, 10.1111/j.1365-2230.2006.02150.x
Treatment of recalcitrant dermatomyositis with efalizumab [3]
In: Acta Dermato-Venereologica, Vol. 86, 2006, Issue 3, S. 254-255, 10.2340/00015555-0058
Rapid growth of invasive metastatic melanoma in carcinogen-treated hepatocyte growth factor/scatter factor-transgenic mice carrying an oncogenic CDK4 mutation
In: American Journal of Pathology, Vol. 169, 2006, Issue 2, S. 665-672, 10.2353/ajpath.2006.060017
Evaluation of DNA vaccination with recombinant adenoviruses using bioluminescence imaging of antigen expression: Impact of application routes and delivery with dendritic cells
In: Journal of Gene Medicine, Vol. 8, 2006, Issue 10, S. 1243-1250, 10.1002/jgm.952
Type I interferon-associated cytotoxic inflammation in lichen planus
In: Journal of Cutaneous Pathology, Vol. 33, 2006, Issue 10, S. 672-678, 10.1111/j.1600-0560.2006.00527.x
Methotrexate treatment in cutaneous lupus erythematosus: Subcutaneous application is as effective as intravenous administration [16]
In: British Journal of Dermatology, Vol. 155, 2006, Issue 4, S. 861-862, 10.1111/j.1365-2133.2006.07431.x
Adenovirus efficiently transduces plasmacytoid dendritic cells resulting in TLR9-dependent maturation and IFN-α production
In: Journal of Gene Medicine, Vol. 8, 2006, Issue 11, S. 1300-1306, 10.1002/jgm.964
Scarring skin lesions of discoid lupus erythematosus are characterized by high numbers of skin-homing cytotoxic lymphocytes associated with strong expression of the type I interferon-induced protein MxA
In: British Journal of Dermatology, Vol. 153, 2005, Issue 5, S. 1011-1015, 10.1111/j.1365-2133.2005.06784.x
Absence of CD26 expression on skin-homing CLA+ CD4+ T lymphocytes in peripheral blood is a highly sensitive marker for early diagnosis and therapeutic monitoring of patients with Sézary syndrome
In: Clinical and Experimental Dermatology, Vol. 30, 2005, Issue 6, S. 702-706, 10.1111/j.1365-2230.2005.01904.x
The role of cytotoxic skin-homing CD8+ lymphocytes in cutaneous cytotoxic T-cell lymphoma and pityriasis lichenoides
In: Journal of the American Academy of Dermatology, Vol. 53, 2005, Issue 3, S. 422-427, 10.1016/j.jaad.2005.05.042
Evidence for a role of type I interferons in the pathogenesis of dermatomyositis [15] (multiple letters)
In: British Journal of Dermatology, Vol. 153, 2005, Issue 2, S. 462-464, 10.1111/j.1365-2133.2005.06786.x
Efficacy and safety of methotrexate in recalcitrant cutaneous lupus erythematosus: Results of a retrospective study in 43 patients
In: British Journal of Dermatology, Vol. 153, 2005, Issue 1, S. 157-162, 10.1111/j.1365-2133.2005.06552.x
Type I interferon-associated recruitment of cytotoxic lymphocytes: A common mechanism in regressive melanocytic lesions
In: American Journal of Clinical Pathology, Vol. 124, 2005, Issue 1, S. 37-48, 10.1309/4EJ9-KL7C-GDEN-VVLE
The expression of human leukocyte antigen-DR and CD25 on circulating T cells in cutaneous lupus erythematosus and correlation with disease activity
In: Experimental Dermatology, Vol. 14, 2005, Issue 6, S. 454-459, 10.1111/j.0906-6705.2005.00301.x
Role of the chemokine receptor CCR4 and its ligand thymus- and activation-regulated chemokine/CCL17 for lymphocyte recruitment in cutaneous lupus erythematosus
In: Journal of Investigative Dermatology, Vol. 124, 2005, Issue 6, S. 1241-1248, 10.1111/j.0022-202X.2005.23755.x
Altered intracellular sorting signals do not influence the efficacy of genetic melanoma vaccines incorporating helper determinants in mice
In: Journal of Gene Medicine, Vol. 7, 2005, Issue 5, S. 613-620, 10.1002/jgm.702
Erratum: Breaking tolerance - Another piece added to the vitiligo puzzle (Journal of Investigative Dermatology (2005) 124 (xiii-xv))
In: Journal of Investigative Dermatology, Vol. 124, 2005, Issue 5, S. 1092, 10.1111/j.0022-202X.2005.23751.x
Successful rituximab treatment of severe Pemphigus vulgaris resistant to multiple immunosuppressants [8]
In: Acta Dermato-Venereologica, Vol. 85, 2005, Issue 2, S. 185-186, 10.1080/00015550410024111
Topical treatment of bullous pemphigoid with tacrolimus. Case report with brief literature review [Topische therapie des bullösen pemphigoids mit tacrolimus. Ein fallbericht mit kurzer übersicht die literatur]
In: JDDG - Journal of the German Society of Dermatology, Vol. 3, 2005, Issue 3, S. 207-210
Impact of p53-based immunization on primary chemically-induced tumors
In: International Journal of Cancer, Vol. 113, 2005, Issue 6, S. 961-970, 10.1002/ijc.20686
Enhanced type I interferon signalling promotes Th1-biased inflammation in cutaneous lupus erythematosus
In: Journal of Pathology, Vol. 205, 2005, Issue 4, S. 435-442, 10.1002/path.1721
Circulating clonal CLA+ and CD4+ T cells in Sézary syndrome express the skin-homing chemokine receptors CCR4 and CCR10 as well as the lymph node-homing chemokine receptor CCR7
In: British Journal of Dermatology, Vol. 152, 2005, Issue 2, S. 258-264, 10.1111/j.1365-2133.2004.06325.x
Peripheral CD8+ T cell tolerance against melanocytic self-antigens in the skin is regulated in two steps by CD4+ T cells and local inflammation: Implications for the pathophysiology of vitiligo
In: Journal of Investigative Dermatology, Vol. 124, 2005, Issue 1, S. 144-150, 10.1111/j.0022-202X.2004.23538.x
Therapeutic effectiveness of recombinant cancer vaccines is associated with a prevalent T-cell receptor α usage by melanoma-specific CD8+ T lymphocytes
In: Cancer Research, Vol. 64, 2004, Issue 21, S. 8068-8076, 10.1158/0008-5472.CAN-04-0067
Successful treatment of recalcitrant Wegener's granulomatosis of the skin with tacrolimus (Prograf™) [1]
In: British Journal of Dermatology, Vol. 151, 2004, Issue 4, S. 927-928, 10.1111/j.1365-2133.2004.06187.x
Early Adenoviral Gene Expression Mediates Immunosuppression by Transduced Dendritic Cell (DC): Implications for Immunotherapy Using Genetically Modified DC
In: Journal of Immunology, Vol. 172, 2004, Issue 3, S. 1524-1530
Initiation and regulation of CD8+T cells recognizing melanocytic antigens in the epidermis: Implications for the pathophysiology of vitiligo
In: European Journal of Cell Biology, Vol. 83, 2004, Issue 11-12, S. 797-803, 10.1078/0171-9335-00423
Systemic treatment of cutaneous lupus erythematosus [Systemische therapie des kutanen lupus erythematodes]
In: JDDG - Journal of the German Society of Dermatology, Vol. 1, 2003, Issue 9, S. 694-704, 10.1046/j.1610-0387.2003.03024.x
Cutaneous lesions in lupus erythematosus [Kutane manifestationen des lupus erythematodes]
In: Deutsche Medizinische Wochenschrift, Vol. 128, 2003, Issue 31-32, S. 1655-1658, 10.1055/s-2003-41095
Transcriptional targeting of dendritic cells for gene therapy using the promoter of the cytoskeletal protein fascin
In: Gene Therapy, Vol. 10, 2003, Issue 12, S. 1035-1040, 10.1038/sj.gt.3301968
Priming of T cells with Ad-transduced DC followed by expansion with peptide-pulsed DC significantly enhances the induction of tumor-specific CD8+ T cells: Implications for an efficient vaccination strategy
In: Gene Therapy, Vol. 10, 2003, Issue 3, S. 243-250, 10.1038/sj.gt.3301880
Interleukin-10-treated dendritic cells modulate immune responses of naive and sensitized T cells In vivo
In: Journal of Investigative Dermatology, Vol. 119, 2002, Issue 4, S. 836-841, 10.1046/j.1523-1747.2002.00496.x
Tumor immunity and autoimmunity: Lessons for the development of modern melanome vaccines learned in murine models [Tumorimmunabwehr und autoimmunität: Erkenntnisse für die entwicklung moderner melanomvakzinen aus tierexperimentellen studien]
In: H+G Zeitschrift fur Hautkrankheiten, Vol. 77, 2002, Issue 11, S. 553-558, 10.1046/j.1439-0353.2002.02604.x
Genetic immunization with a melanocytic self-antigen linked to foreign helper sequences breaks tolerance and induces autoimmunity and tumor immunity
In: Gene Therapy, Vol. 9, 2002, Issue 3, S. 208-213, 10.1038/sj/gt/3301634
Efficacy of recombinant adenovirus as vector for allergen gene therapy in a mouse model of type I allergy
In: Gene Therapy, Vol. 9, 2002, Issue 2, S. 147-156, 10.1038/sj/gt/3301625
Adenovirus-transduced dendritic cells stimulate cellular immunity to melanoma via a CD4+ T cell-dependent mechanism
In: Gene Therapy, Vol. 8, 2001, Issue 16, S. 1255-1263, 10.1038/sj.gt.3301521
A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection
In: International Journal of Cancer, Vol. 93, 2001, Issue 2, S. 243-251, 10.1002/ijc.1323
Depletion of CD25+ CD4+ T cells and treatment with tyrosinase-related protein 2-transduced dendritic cells enhance the interferon α-induced, CD8+ T-cell-dependent immune defense of B16 melanoma
In: Cancer Research, Vol. 61, 2001, Issue 24, S. 8643-8646
Immunogenicity of enhanced green fluorescent protein (EGFP) in BALB/c mice: Identification of an H2-Kd-restricted CTL epitope
In: Gene Therapy, Vol. 7, 2000, Issue 23, S. 2036-2040, 10.1038/sj.gt.3301335
Induction of dendritic cell maturation and modulation of dendritic cell-induced immune responses by prostaglandins
In: Archives of Dermatological Research, Vol. 292, 2000, Issue 9, S. 437-445
Genetic immunization of mice with human tyrosinase-related protein 2: Implications for the immunotherapy of melanoma
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Efficient transduction of mature CD83+ dendritic cells using recombinant adenovirus suppressed T cell stimulatory capacity
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IFN-α-expressing tumor cells enhance generation and promote survival of tumor-specific CTLs
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Induction of tumor antigen-specific immunity using plasmid DNA immunization in mice
In: Cancer Gene Therapy, Vol. 6, 1999, Issue 1, S. 73-80
Interferon-alpha gene therapy in combination with CD80 transduction reduces tumorigenicity and growth of established tumor in poorly immunogenic tumor models
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Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12
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Dendritic Cell-based Genetic Immunization in Mice with a Recombinant Adenovirus Encoding Murine TRP2 Induces Effective Anti-melanoma Immunity
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The immunology of cutaneous DNA immunization
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Co-delivery of T helper 1-biasing cytokine genes enhances the efficacy of gene gun immunization of mice: Studies with the model tumor antigen β-galactosidase and the BALB/c Meth A p53 tumor-specific antigen
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Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro: Enhancement by cotransfection of genes encoding the Th1-biasing cytokines IL-12 and IFN-α
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DNA vaccines targeting dendritic cells for the immunotherapy of cancer
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DNA immunization targeting the skin: Molecular control of adaptive immunity
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Development of dendritic cell-based genetic vaccines for cancer
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Genetically modified bone marrow-derived dendritic cells expressing tumor-associated viral or 'self' antigens induce antitumor immunity in vivo
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Interferon-α gene therapy for cancer: Retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models
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Gene-based strategies for the immunotherapy of cancer
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Universitätshautklinik
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