UNIVERSITÄTSHAUTKLINIK

Klinikdirektor Prof. Dr.T.Tüting

Klinikdirektor

Prof. Dr. med. Thomas Tüting

Universitätshautklinik (KHAU)
Haus 14, Leipziger Straße 44, 39120, Magdeburg,
Publikationen

2024

Buchbeitrag

Kreher, Robert; Chitti, Naveeth Reddy; Hille, Georg; Hürtgen, Janine; Mengoni, Miriam; Braun, Andreas; Tüting, Thomas; Preim, Bernhard; Saalfeld, Sylvia

Advanced deep learning for skin histoglyphics at cellular level
In: Bildverarbeitung für die Medizin 2024 - Wiesbaden : Springer Fachmedien Wiesbaden ; Maier, Andreas *1980-*, S. 66-71

2023

Buchbeitrag

Mengoni, Miriam; Tüting, Thomas

Malignes Melanom
In: DGIM Innere Medizin , Living Reference Work, continuously updated edition - Berlin, Heidelberg : Springer ; Lehnert, Hendrik *1954-* . - 2023, S. 1-8

Begutachteter Zeitschriftenartikel

Krug, Julia; Rodrian, Gabriele; Petter, Katja; Yang, Hai; Khoziainova, Svetlana; Guo, Wei; Bénard, Alan; Merkel, Susanne; Gellert, Susan; Maschauer, Simone; Spermann, Monika; Waldner, Maximilian Josef; Bailey, Peter; Pilarsky, Christian; Liebl, Andrea; Tripal, Philipp; Christoph, Jan; Naschberger, Elisabeth; Croner, Roland; Schellerer, Vera Simone Angela; Becker, Christoph; Hartmann, Arndt; Tüting, Thomas; Prante, Olaf; Grützmann, Robert; Grivennikov, Sergei I.; Stürzl, Michael; Britzen-Laurent, Nathalie

N-glycosylation regulates intrinsic IFN-γ resistance in colorectal cancer - implications for immunotherapy
In: Gastroenterology - Stanford, Calif. : HighWire Press, Bd. 164 (2023), Heft 3, S. 392-406.e5

Begutachteter Zeitschriftenartikel

Mengoni, Miriam; Braun, Andreas; Hinnerichs, Mattes; Tüting, Thomas; Surov, Alexey

Subcutaneous fat abundance and density are associated with an enhanced response to immunotherapy in metastatic melanoma - a retrospective cohort study
In: Academic radiology - Philadelphia, PA [u.a.] : Elsevier, Bd. 30 (2023), Heft Supplement 1, S. S257-S267

Begutachteter Zeitschriftenartikel

Mengoni, Miriam; Braun, Andreas; Has, Cristina; Tüting, Thomas; Gaffal, Evelyn

Acantholytic squamous cell carcinoma in a patient with junctional epidermolysis bullosa - Akantholytisches Plattenepithelkarzinom bei einer Patientin mit junktionaler Epidermolysis bullosa
In: Journal der Deutschen Dermatologischen Gesellschaft / Deutsche Dermatologische Gesellschaft - Berlin : Wiley-Blackwell, Bd. 21 (2023), Heft 7, S. 798-801

Begutachteter Zeitschriftenartikel

Kruse, Bastian; Buzzai, Anthony C.; Shridhar, Naveen; Braun, Andreas; Gellert, Susan; Knauth, Kristin; Pozniak, Joanna; Peters, Johannes; Dittmann, Paulina; Mengoni, Miriam; Sluis, Tetje Cornelia; Höhn, Simon; Antoranz, Asier; Krone, Anna; Fu, Yan; Yu, Di; Essand, Magnus; Geffers, Robert; Mougiakakos, Dimitrios; Kahlfuß, Sascha; Kashkar, Hamid; Gaffal, Evelyn; Bosisio, Francesca M.; Bechter, Oliver; Rambow, Florian; Marine, Jean-Christophe; Kastenmüller, Wolfgang; Müller, Andreas Johann; Tüting, Thomas

CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours
In: Nature - London [u.a.] : Nature Publ. Group, Bd. 618 (2023), Heft 7967, S. 1033-1040

2022

Begutachteter Zeitschriftenartikel

Effern, Maike; Glodde, Nicole Erika; Bawden, Emma; Liebing, Jana; Hinze, Daniel; Tüting, Thomas; Gebhardt, Thomas; Hölzel, Michael

CRISPitope - a generic platform to model target antigens for adoptive T cell transfer therapy in mouse tumor models
In: STAR Protocols - Cambridge, MA: Cell Press, 2020, Bd. 3 (2022), 1, insges. 28 S.

Begutachteter Zeitschriftenartikel

Mengoni, Miriam; Tüting, Thomas; Gaffal, Evelyn

Kognitive Funktionsstörungen unter Systemtherapie bei metastasiertem Melanom - Immunological mechanisms of cognitive dysfunction under systemic therapy in metastatic melanoma
In: Die Dermatologie - [Berlin]: Springer Medizin Verlag GmbH, Bd. 73 (2022), 12, S. 937-942

Begutachteter Zeitschriftenartikel

Garbe, Claus; Keim, Ulrike; Amaral, Teresa; Berking, Carola; Eigentler, Thomas; Flatz, Lukas; Gesierich, Anja Heike; Leiter-Stöppke, Ulrike; Stadler, Rudolf; Sunderkötter, Cord; Tüting, Thomas; Utikal, Jochen; Wollina, Uwe; Zimmer, Lisa; Zouboulis, Christos C.; Ascierto, Paolo; Eggermont, Alexander; Grob, Jean-Jacques; Hauschild, Axel; Sekulovic, Lidija Kandolf; Long, Georgina; Luke, Jason; Michielin, Olivier; Peris, Ketty; Schadendorf, Dirk; Kirkwood, John M.; Lorigan, Paul C.

Prognosis of patients with primary melanoma stage I and II according to American Joint Committee on Cancer version 8 validated in two independent cohorts - implications for adjuvant treatment
In: Journal of clinical oncology - Alexandria, Va. : American Society of Clinical Oncology, Bd. 40 (2022), Heft 32, S. 3741-3749, insges. 13 S.

Begutachteter Zeitschriftenartikel

Liu, Xiaobo; Wang, Yuanyuan; Bauer, Alexander; Kirschfink, Michael; Ding, Peipei; Gebhardt, Christoffer; Borsig, Lubor; Tüting, Thomas; Renné, Thomas; Häffner, Karsten; Hu, Weiguo; Schneider, Stefan W.; Gorzelanny, Christian

Neutrophils activated by membrane attack complexes increase the permeability of melanoma blood vessels
In: Proceedings of the National Academy of Sciences of the United States of America/ National Academy of Sciences - Washington, DC: National Acad. of Sciences, Bd. 119 (2022), Heft 33, S. 1-12, Artikel e2122716119, insges. 12 S.

Begutachteter Zeitschriftenartikel

Daoud, Mila; Broxtermann, Pia Nora; Schorn, Fabian; Werthenbach, J. Paul; Seeger, Jens Michael; Schiffmann, Lars Mortimer; Brinkmann, Kerstin; Vucic, Domagoj; Tüting, Thomas; Mauch, Cornelia; Kulms, Dagmar; Zigrino, Paola; Kashkar, Hamid

XIAP promotes melanoma growth by inducing tumour neutrophil infiltration
In: EMBO reports/ European Molecular Biology Organization - Heidelberg: EMBO Press, 2000, Bd. 23 (2022), 6, insges. 15 S.

Begutachteter Zeitschriftenartikel

Mengoni, Miriam; Lenz, Freya-Sophie; Braun, Andreas; Tüting, Thomas; Gaffal, Evelyn

Persistent facial swelling - Persistierende Schwellung des Gesichts
In: Journal der Deutschen Dermatologischen Gesellschaft/ Deutsche Dermatologische Gesellschaft - Berlin: Wiley-Blackwell, Bd. 20 (2022), 7, S. 1033-1036

Begutachteter Zeitschriftenartikel

Böttcher, Martin; Böttcher-Loschinski, Romy; Kahlfuß, Sascha; Aigner, Michael; Gießl, Andreas; Mackensen, Andreas; Schlötzer-Schrehardt, Ursula; Tüting, Thomas; Bruns, Heiko; Mougiakakos, Dimitrios

CLL-derived extracellular vesicles impair T-cell activation and foster T-cell exhaustion via multiple immunological checkpoints
In: Cells - Basel : MDPI, Bd. 11 (2022), Heft 14, Artikel 2176, insges. 20 S.

Begutachteter Zeitschriftenartikel

Rogava, Meri; Braun, Andreas; Sluis, Tetje Cornelia; Shridhar, Naveen; Tüting, Thomas; Gaffal, Evelyn

Tumor cell intrinsic Toll-like receptor 4 signaling promotes melanoma progression and metastatic dissemination
In: International journal of cancer - Bognor Regis: Wiley-Liss, 1966, Bd. 150 (2022), 1, S. 142-151

Artikel in Kongressband

Bostelmann-Arp, Lukas; Mostaghim, Sanaz; Braun, Andreas; Tüting, Thomas

Multi-objective evolutionary game theory - a case study in cancer therapy
In: Konferenz: Conference on Artificial Life, ALIFE 2022, online, July 18-22, 2022, Proceedings of the Artificial Life Conference 2022, ALIFE, 2022; Holler, Silvia . - 2022, insges. 3 S.

Nicht begutachteter Zeitschriftenartikel

Hass, Peter; Gawish, Ahmed; Thele, Franziska; Tüting, Thomas; Ignatov, Atanas; Brunner, Thomas B.

Unterschätzte Technik - Die kombinierte Oberflächenhyperthermie/hypofraktionierte Radiotherapie (HRT) für lokal rezidivierte Mammakarzinome, Plattenepithelkarzinome sowie Basalzellkarzinome der Haut
In: Ärzteblatt Sachsen-Anhalt - offizielles Mitteilungsblatt der Ärztekammer Sachsen-Anhalt - Magdeburg: Ärztekammer Sachsen-Anhalt, Bd. 33 (2022), 11, S. 25-28

2021

Begutachteter Zeitschriftenartikel

Ruotsalainen, Janne; López Ramos, Dorys Adriana; Rogava, Meri; Shridhar, Naveen; Glodde, Nicole Erika; Gaffal, Evelyn; Hölzel, Michael; Bald, Tobias; Tüting, Thomas

The myeloid cell type I IFN system promotes antitumor immunity over pro-tumoral inflammation in cancer T-cell therapy
In: Clinical & Translational Immunology - Hoboken, NJ: Wiley, 2012, Bd. 10 (2021), insges. 14 S.

Begutachteter Zeitschriftenartikel

Ottina, Eleonora; Panova, Veera; Doglio, Laura; Kazachenka, Anastasiya; Cornish, Georgina; Kirkpatrick, Joanna; Attig, Jan; Young, George R.; Litchfield, Kevin; Lesluyes, Tom; Loo, Peter; Swanton, Charles; MacRae, James; Tüting, Thomas; Kassiotis, George

E3 ubiquitin ligase HECTD2 mediates melanoma progression and immune evasion
In: Oncogene - London: Springer Nature, 1997, Bd. 40 (2021), 37, S. 5567-5578

Begutachteter Zeitschriftenartikel

Mengoni, Miriam; Tüting, Thomas; Gaffal, Evelyn

Photokarzinogenese - Molekulare Mechanismen und praktische Relevanz
In: Der Hautarzt: Organ der Deutschen Dermatologischen Gesellschaft - Berlin: Springer, Bd. 72 (2021), 1, S. 6-13

2020

Artikel in Zeitschrift

Garbe, Claus; Keim, Ulrike; Suciu, Stefan; Amaral, Teresa; Eigentler, Thomas; Gesierich, Anja Heike; Hauschild, Axel; Heinzerling, Lucie; Kiecker, Felix; Schadendorf, Dirk; Stadler, Rudolf; Sunderkötter, Cord; Tüting, Thomas; Utikal, Jochen; Wollina, Uwe; Zouboulis, Christos C.; Keilholz, Ulrich; Testori, Alessandro; Martus, Peter; Leiter-Stöppke, Ulrike; Eggermont, Alexander

Prognosis of patients with stage III melanoma according to American Joint Committee on Cancer version 8 - a reassessment on the basis of 3 independent stage III melanoma cohorts
In: Journal of clinical oncology - Alexandria, Va.: American Society of Clinical Oncology, 1983, Bd. 38 (2020), 22, S. 2543-2551, insges. 9 S.

Buchbeitrag

Steinhauer, Nastasja; Horbrügger, Marc; Braun, Andreas; Tüting, Thomas; Oeltze-Jafra, Steffen; Müller, Juliane

Comprehensive visualization of longitudinal patient data for the dermatological oncological tumor board
In: EuroVis 2020 - Eurographics Association; Kerren, Andreas . - 2020, S. 169-173

Begutachteter Zeitschriftenartikel

Fuchs, Felix; Franke, Ingolf; Tüting, Thomas; Gaffal, Evelyn

Successful treatment of non-uremic calciphylaxis with bisphosphonate. Clinical letter
In: Journal der Deutschen Dermatologischen Gesellschaft/ Deutsche Dermatologische Gesellschaft - Berlin: Wiley-Blackwell, Bd. 18 (2020), 12, S. 1498-1500

Begutachteter Zeitschriftenartikel

Effern, Maike; Glodde, Nicole Erika; Braun, Matthias; Liebing, Jana; Boll, Helena N.; Yong, Michelle; Bawden, Emma; Hinze, Daniel; Boorn-Konijnenberg, Debby; Daoud, Mila; Aymans, Pia; Landsberg, Jennifer Caroline; Smyth, Mark J.; Flatz, Lukas; Tüting, Thomas; Bald, Tobias; Gebhardt, Thomas; Hölzel, Michael

Adoptive T cell therapy targeting different gene products reveals diverse and context-dependent immune evasion in melanoma
In: Immunity - [Cambridge, Mass.]: Cell Press, 1994, Bd. 53.2020, 3, S. 564-580.e9

Begutachteter Zeitschriftenartikel

Amaral, Teresa; Kiecker, Felix; Schäfer, Sarah; Stege, Henner Maximilian; Kähler, Katharina C.; Terheyden, Patrick; Gesierich, Anja Heike; Gutzmer, Ralf; Haferkamp, Sebastian; Utikal, Jochen; Berking, Carola; Rafei-Shamsabadi, David Ali; Reinhardt, Lydia; Meier, Friedegund; Karoglan, Ante; Posch, Christian; Gambichler, Thilo; Pföhler, Claudia Ursula; Thoms, Kai-Martin; Tietze, Julia Katharina; Debus, Dirk; Herbst, Rudolf; Emmert, Steffen; Loquai, Carmen; Hassel, Jessica C.; Meiß, Frank; Tueting, Thomas; Heinrich, Vanessa; Eigentler, Thomas; Garbe, Claus; Zimmer, Lisa

Combined immunotherapy with nivolumab and ipilimumab with and without local therapy in patients with melanoma brain metastasis - a DeCOG* study in 380 patients
In: Journal for ImmunoTherapy of Cancer: official journal of the Society for Immunotherapy of Cancer (SITC) - London: BioMed Central, 2013, Vol. 8.2020,1, Artikel-Nummer e000333, 11 Seiten[Gesehen am 06.10.2020]

Begutachteter Zeitschriftenartikel

Gaffal, Evelyn; Kemter, Andrea M.; Scheu, Stefanie; Leite Dantas, Rafael; Vogt, Jens; Baune, Bernhard Th.; Tüting, Thomas; Zimmer, Andreas; Alferink, Judith

Cannabinoid receptor 2 modulates maturation of dendritic cells and their capacity to induce hapten-induced contact hypersensitivity
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 2, Art.-Nr, 475, insgesamt 12 Seiten

Begutachteter Zeitschriftenartikel

Braun, Andreas; Mengoni, Miriam; Bonifatius, Susanne; Tüting, Thomas; Gaffal, Evelyn

Activated Hgf-Met signaling cooperates with oncogenic BRAF to drive primary cutaneous melanomas and angiotropic lung metastases in mice
In: The journal of investigative dermatology - Amsterdam: Elsevier, Bd. 140 (2020), 7, S. 1410-1417.e2

Begutachteter Zeitschriftenartikel

Mengoni, Miriam; Braun, Andreas; Gaffal, Evelyn; Tüting, Thomas

The aryl hydrocarbon receptor promotes inflammation-induced dedifferentiation and systemic metastatic spread of melanoma cells
In: International journal of cancer - Bognor Regis: Wiley-Liss, 1966, Bd. 147 (2020), 10, S. 2902-2913

2019

Artikel in Zeitschrift

Gassenmaier, Maximilian; Keim, Ulrike; Leiter-Stöppke, Ulrike; Eigentler, Thomas; Röcken, Martin; Gesierich, Anja Heike; Moritz, Rose Kathrin Caroline; Heinzerling, Lucie; Tüting, Thomas; Wollina, Uwe; Garbe, Claus

Age as key factor for pattern, timing and extent of distant metastasis in patients with cutaneous melanoma - a study of the German Central Malignant Melanoma Registry
In: Journal of the American Academy of Dermatology/ American Academy of Dermatology - Amsterdam [u.a.]: Elsevier, 1979, Bd. 80 (2019), 5, S. 1299-1307.e7

Begutachteter Zeitschriftenartikel

Braun, Andreas; Franke, Ingolf; Tüting, Thomas; Gaffal, Evelyn

Pancreatic panniculitis with polyarthritis (PPP syndrome) - clinical letter
In: Journal der Deutschen Dermatologischen Gesellschaft/ Deutsche Dermatologische Gesellschaft - Berlin: Wiley-Blackwell, Bd. 17 (2019), 5, S. 546-547

Begutachteter Zeitschriftenartikel

Ruotsalainen, Janne; Tüting, Thomas

Live or let die - T cell survival in cancer immunotherapy
In: Immunity - [Cambridge, Mass.]: Cell Press, Bd. 50.2019, 2, S. 280-282

Begutachteter Zeitschriftenartikel

Park, Simone L.; Buzzai, Anthony; Rautela, Jai; Hor, Jyh Liang; Hochheiser, Katharina; Effern, Maike; McBain, Nathan; Wagner, Teagan; Edwards, Jarem; McConville, Robyn; Wilmott, James S.; Scolyer, Richard A.; Tüting, Thomas; Palendira, Umaimainthan; Gyorki, David; Mueller, Scott N.; Huntington, Nicholas D.; Bedoui, Sammy; Hölzel, Michael; Mackay, Laura K.; Waithman, Jason; Gebhardt, Thomas

Tissue-resident memory CD8+ T cells promote melanoma-immune equilibrium in skin
In: Nature - London [u.a.]: Nature Publ. Group, Bd. 565.2019, 7739, S. 366-371, insges. 23 S.

Begutachteter Zeitschriftenartikel

Ulrich, Maximilian; Tinschert, Sigrid; Siebert, Eberhard; Franke, Ingolf; Tüting, Thomas; Ulrich, Jens; Schanze, Denny; Wieland, Ilse; Zenker, Martin

Detection of a multilineage mosaic NRAS mutation c.181C>A (p.Gln61Lys) in an individual with a complex congenital nevus syndrome. Letter to the editor
In: Pigment cell & melanoma research - Oxford [u.a.]: Wiley-Blackwell, Bd. 32.2019, 3, S. 470-473

Begutachteter Zeitschriftenartikel

Karoglan, Ante; Paetzold, Bernhard; Pereira, Joao; Brüggemann, Holger; Tüting, Thomas; Schanze, Denny; Güell, Marc; Gollnick, Harald

Safety and efficacy of topically applied selected Cutibacterium acnes strains over five weeks in patients with acne vulgaris - an open-label, pilot study
In: Acta dermato-venereologica - Uppsala: Acta Dermato-Venereologica, 1946, Bd. 99 (2019), 13, S. 1253-1257

Begutachteter Zeitschriftenartikel

Vogeley, Christian; Esser, Charlotte; Tüting, Thomas; Krutmann, Jean; Haarmann-Stemmann, Thomas

Role of the aryl hydrocarbon receptor in environmentally induced skin aging and skin carcinogenesis
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd.20.2019, 23, Art.-Nr. 6005, insges. 21 S.

Begutachteter Zeitschriftenartikel

Eyerich, Kilian; Tüting, Thomas

Personalisierte Medizin
In: Der Hautarzt: Organ der Deutschen Dermatologischen Gesellschaft - Berlin: Springer, Bd. 70.2019, 1, S. 4

Begutachteter Zeitschriftenartikel

Annala, Suvi; Feng, Xiaodong; Shridhar, Naveen; Eryilmaz, Funda; Patt, Julian; Yang, JuHee; Pfeil, Eva M.; Cervantes-Villagrana, Rodolfo Daniel; Inoue, Asuka; Häberlein, Felix; Slodczyk, Tanja; Reher, Raphael; Kehraus, Stefan; Monteleone, Stefania; Schrage, Ramona; Heycke, Nina; Rick, Ulrike; Engel, Sandra; Pfeifer, Alexander; Kolb, Peter; König, Gabriele M.; Bünemann, Moritz; Tüting, Thomas; Vázquez-Prado, José; Gutkind, J. Silvio; Gaffal, Evelyn; Kostenis, Eva

Direct targeting of Gαq and Gα11 oncoproteins in cancer cells
In: Science signaling - Washington, DC [u.a.]: Assoc., Bd. 12.2019, 573, eaau5948, insges. 14 S.

Begutachteter Zeitschriftenartikel

Bender-Saebelkampf, Sophia; Franke, Ingolf; Alter, Mareike; Tueting, Thomas; Gaffal, Evelyn

Cutaneous and pulmonary botryomycosis
In: The lancet / Infectious diseases - New York, NY: Elsevier, Bd. 19.2019, 6, S. 670

2018

Artikel in Zeitschrift

Teramoto, Yukiko; Keim, Ulrike; Gesierich, Anja Heike; Schuler, Gerold; Fiedler, Eckhard; Tüting, Thomas; Ulrich, Claas; Wollina, Uwe; Hassel, Jessica C.; Gutzmer, Ralf; Goerdt, Sergij; Zouboulis, Christos C.; Leiter-Stöppke, Ulrike; Eigentler, Thomas; Garbe, Claus

Acral lentiginous melanoma - a skin cancer with unfavourable prognostic features : a study of the German Central Malignant Melanoma Registry (CMMR) in 2050 patients
In: British journal of dermatology - Oxford: Wiley-Blackwell, 1892, Bd. 178 (2018), 2, S. 443-451

Begutachteter Zeitschriftenartikel

Ottina, Eleonora; Levy, Prisca; Eksmond, Urszula; Merkenschlager, Julia; Young, George R.; Roels, Juliette; Stoye, Jonathan P.; Tüting, Thomas; Calado, Dinis P.; Kassiotis, George

Restoration of endogenous retrovirus infectivity impacts mouse cancer models
In: Cancer immunology research: illuminating the interplay of cancer and the immune system - Philadelphia, Pa: AACR, Bd. 6.2018, 11, S. 1292-1300

Begutachteter Zeitschriftenartikel

Weyden, Louise; Arends, Mark J.; Brenn, Thomas; Tüting, Thomas; Adams, David J.

Widespread spontaneous hyperproliferation, melanosis and melanoma in Hgf-Cdk4R24C mice. Letter to the editor
In: Melanoma research - Hagerstown, Md. : Lippincott Williams & Wilkins, Bd. 28.2018, 1, S. 76-78

Begutachteter Zeitschriftenartikel

Kunz, Manfred; Löffler-Wirth, Henry; Dannemann, Michael; Willscher, Edith; Doose, Gero; Kelso, Janet; Kottek, Tina; Nickel, Birgit; Hopp, Lydia; Landsberg, Jenny; Hoffmann, Steve; Tüting, Thomas; Zigrino, Paola; Mauch, Cornelia; Utikal, Jochen; Ziemer, Mirjana; Schulze, Hans-Joachim; Hölzel, Michael; Rösch, Alexander Oliver; Kneitz, Susanne; Meierjohann, Svenja; Bosserhoff, Anja-Katrin; Binder, Hans; Schartl, Manfred

RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas
In: Oncogene - London: Springer Nature, 1997, Bd. 37.2018, 47, S. 6136-6151, insges. 15 S.[Gesehen am 13.11.2019]

Begutachteter Zeitschriftenartikel

Schiefer, Jan; Gröne, Hermann-Josef; Tüting, Thomas; Chatzikyrkou, Christos; Mertens, Peter Rene

Von Hauteffloreszenzen zum pulmorenalen Syndrom - Eine überraschende Ursache für eine systemische Vaskulitis
In: Der Nephrologe: Zeitschrift für Nephrologie und Hypertensiologie - Berlin: Springer, Bd. 13.2018, 6, S. 411-415

2017

Begutachteter Zeitschriftenartikel

Falletta, Paola; Sanchez-del-Campo, Luis; Chauhan, Jagat; Effern, Maike; Kenyon, Amy; Kershaw, Christopher J.; Siddaway, Robert; Lisle, Richard; Freter, Rasmus; Daniels, Matthew J.; Lu, Xin; Tüting, Thomas; Middleton, Mark; Buffa, Francesca M.; Willis, Anne E.; Pavitt, Graham; Ronai, Ze'ev A.; Sauka-Spengler, Tatjana; Hölzel, Michael; Goding, Colin R.

Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma
In: Genes & development - Stanford, Calif: HighWire Press, Bd. 31 (2017), 1, S. 18-33

Begutachteter Zeitschriftenartikel

Weyden, Louise; Arends, Mark J.; Campbell, Andrew D.; Bald, Tobias; Wardle-Jones, Hannah; Griggs, Nicola; Castillo Velasco-Herrera, Martin; Tüting, Thomas; Sansom, Owen J.; Karp, Natasha A.; Clare, Simon; Gleeson, Diane; Ryder, Edward; Galli, Antonella; Tuck, Elizabeth; Cambridge, Emma L.; Voet, Thierry; Macaulay, Iain C.; Wong, Kim; Spiegel, Sarah; Speak, Anneliese O.; Adams, David J.

Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. Letter
In: Nature - London [u.a.]: Nature Publ. Group, Bd. 541 (2017), 7636, S. 233-236

Begutachteter Zeitschriftenartikel

Glodde, Nicole Erika; Bald, Tobias; Boorn-Konijnenberg, Debby; Nakamura, Kyohei; ODonnell, Jake S.; Szczepanski, Sabrina; Brandes, Maria; Eickhoff, Sarah; Das, Indrajit; Shridhar, Naveen; Hinze, Daniel; Rogava, Meri; Sluis, Tetje C.; Ruotsalainen, Janne J.; Gaffal, Evelyn; Landsberg, Jennifer Caroline; Ludwig, Kerstin U.; Wilhelm, Christoph; Riek-Burchardt, Monika; Müller, Andreas Johann; Gebhardt, Christoffer; Scolyer, Richard A.; Long, Georgina; Janzen, Viktor; Teng, Michele W.L.; Kastenmüller, Wolfgang; Mazzone, Massimiliano; Smyth, Mark J.; Tüting, Thomas; Hölzel, Michael

Reactive neutrophil responses dependent on the receptor tyrosine kinase c-MET limit cancer immunotherapy
In: Immunity - [Cambridge, Mass.]: Cell Press, Bd. 47 (2017), 4, S. 789-802

Begutachteter Zeitschriftenartikel

Layer, Julian P.; Kronmüller, Marie T.; Quast, Thomas Wilhelm; Boorn-Konijnenberg, Debby; Effern, Maike; Hinze, Daniel; Althoff, Kristina; Schramm, Alexander; Westermann, Frank; Peifer, Martin; Hartmann, Gunther; Tüting, Thomas; Kolanus, Waldemar; Fischer, Matthias; Schulte, Johannes; Hölzel, Michael

Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression
In: OncoImmunology - Abingdon: Taylor & Franics, Bd. 6 (2017), 6

Begutachteter Zeitschriftenartikel

Giebeler, Nives; Schönefuß, Alexander; Landsberg, Jennifer Caroline; Tüting, Thomas; Mauch, Cornelia; Zigrino, Paola

Deletion of ADAM-9 in HGF/CDK4 mice impairs melanoma development and metastasis
In: Oncogene - London: Springer Nature, Bd. 36 (2017), 35, S. 5058-5067

Begutachteter Zeitschriftenartikel

Reinhardt, Julia; Landsberg, Jennifer Caroline; Schmid-Burgk, Jonathan; Ramis, Bartomeu Bibiloni; Bald, Tobias; Glodde, Nicole Erika; López Ramos, Dorys Adriana; Young, Arabella; Ngiow, Shin Foong; Nettersheim, Daniel; Schorle, Hubert; Quast, Thomas Wilhelm; Kolanus, Waldemar; Schadendorf, Dirk; Long, Georgina; Madore, Jason; Scolyer, Richard A.; Ribas, Antoni; Smyth, Mark J.; Tumeh, Paul C.; Tüting, Thomas; Hölzel, Michael

MAPK Signaling and Inflammation Link Melanoma Phenotype Switching to Induction of CD73 during Immunotherapy
In: Cancer research - Philadelphia, Pa: AACR, Bd. 77 (2017), 17, S. 4697-4709

Begutachteter Zeitschriftenartikel

Engel, Christina; Brügmann, Grethe; Lambing, Silke; Mühlenbeck, Larissa Helen; Marx, Samira; Hagen, Christian; Horváth, Dorottya; Goldeck, Marion; Ludwig, Janos; Herzner, Anna-Maria; Drijfhout, Jan W.; Wenzel, Daniela; Coch, Christoph; Tüting, Thomas; Schlee, Martin; Hornung, Veit; Hartmann, Gunther; Boorn, Jasper G.

RIG-I resists hypoxia-induced immunosuppression and dedifferentiation
In: Cancer immunology research: illuminating the interplay of cancer and the immune system - Philadelphia, Pa.: AACR, 2013, Bd. 5.2017, 6, S. 455-467

Begutachteter Zeitschriftenartikel

Mescher, Melina; Jeong, Peter; Knapp, Sina K.; Rübsam, Matthias; Saynisch, Michael; Kranen, Marina; Landsberg, Jennifer Caroline; Schlaak, Max Simon; Mauch, Cornelia; Tüting, Thomas; Niessen, Carien M.; Iden, Sandra

The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma
In: Journal of experimental medicine: JEM - New York, NY: Rockefeller Univ. Press, Bd. 214.2017, 2, S. 339-358

Begutachteter Zeitschriftenartikel

Sektioglu, Ibrahim Murathan; Carretero, Rafael; Bulbuc, Nadja; Bald, Tobias; Tüting, Thomas; Rudensky, Alexander Y.; Hämmerling, Günter J.

Basophils promote tumor rejection via chemotaxis and infiltration of CD8+ T cells
In: Cancer research - Philadelphia, Pa: AACR, 1916, Bd. 77.2017, 2, S. 291-302

2016

Begutachteter Zeitschriftenartikel

Knappe, Nathalie; Novak, Daniel; Weina, Kasia; Bernhardt, Mathias; Reith, Maike; Larribere, Lionel; Hölzel, Michael; Tüting, Thomas; Gebhardt, Christoffer; Umansky, Viktor; Utikal, Jochen

Directed Dedifferentiation Using Partial Reprogramming Induces Invasive Phenotype in Melanoma Cells
In: STEM CELLS, 2016, S. 832-846, ISSN 10665099, 10.1002/stem.2284

Begutachteter Zeitschriftenartikel

Hölzel, Michael; Tüting, Thomas

Inflammation-induced plasticity in melanoma therapy and metastasis
In: Trends in immunology. - Amsterdam [u.a.] : Elsevier Science, Bd. 37.2016, 6, S. 364-374

Begutachteter Zeitschriftenartikel

Reuten, Raphael; Patel, Trushar R.; McDougall, Matthew; Rama, Nicolas; Nikodemus, Denise; Gibert, Benjamin; Delcros, Jean-Guy; Prein, Carina; Meier, Markus; Metzger, Stéphanie; Zhou, Zhigang; Kaltenberg, Jennifer; McKee, Karen K.; Bald, Tobias; Tüting, Thomas; Zigrino, Paola; Djonov, Valentin; Bloch, Wilhelm; Clausen-Schaumann, Hauke; Poschl, Ernst; Yurchenco, Peter D.; Ehrbar, Martin; Mehlen, Patrick; Stetefeld, Jörg; Koch, Manuel

Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes
In: Nature Communications - [London]: Nature Publishing Group UK, 2010, Bd. 7.2016, Art.-Nr. 13515, insges. 17 S.

Begutachteter Zeitschriftenartikel

Tüting, Thomas

Die tumorimmunologische Revolution in der Behandlung des fortgeschrittenen Melanoms. Editorial
In: Journal der Deutschen Dermatologischen Gesellschaft : JDDG. - Berlin : Wiley-Blackwell, Bd. 14.2016, 7, S. 655-656

Begutachteter Zeitschriftenartikel

Baar, Martina; Coquille, Loren; Mayer, Hannah; Hölzel, Michael; Rogava, Meri; Tüting, Thomas; Bovier, Anton

A stochastic model for immunotherapy of cancer
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 6.2016, Art.-Nr. 24169, insges. 10 S.

Begutachteter Zeitschriftenartikel

Tüting, Thomas; Visser, Karin E. de

How neutrophils promote metastasis - Neutrophils may be cellular targets for cancer therapy
In: Science. - Washington, DC [u.a.] : American Association for the Advancement of Science, Bd. 352.2016, 6282, S. 145-146

Begutachteter Zeitschriftenartikel

Hölzel, Michael; Landsberg, Jennifer; Glodde, Nicole; Bald, Tobias; Rogava, Meri; Riesenberg, Stefanie; Becker, Albert; Jönsson, Göran; Tüting, Thomas

A Preclinical Model of Malignant Peripheral Nerve Sheath Tumor-like Melanoma Is Characterized by Infiltrating Mast Cells
In: Cancer Research, 2016, S. 251-263, ISSN 0008-5472, 10.1158/0008-5472.CAN-15-1090

Begutachteter Zeitschriftenartikel

Kilian, Marta M.; Herwig, Martina C.; Holz, Frank G.; Tüting, Thomas; Loeffler, Karin U.

Overexpression of hepatocyte growth factor and an oncogenic CDK4 variant in mice alters corneal stroma morphology but does not lead to spontaneous ocular melanoma
In: Melanoma Research, 2016, S. 89-91, ISSN 0960-8931, 10.1097/CMR.0000000000000206

2015

Begutachteter Zeitschriftenartikel

Bald, Tobias; Landsberg, Jennifer; Jansen, Philipp; Gaffal, Evelyn; Tüting, Thomas

Phorbol ester-induced neutrophilic inflammatory responses selectively promote metastatic spread of melanoma in a TLR4-dependent manner
In: OncoImmunology, 2015, S. e1078964, ISSN 2162-402X, 10.1080/2162402X.2015.1078964

Begutachteter Zeitschriftenartikel

Glodde, N.; Jakobs, M.; Bald, T.; Tüting, T.; Gaffal, E.

Differential role of cannabinoids in the pathogenesis of skin cancer
In: Life Sciences, Vol. 138, 2015, S. 35-40, 10.1016/j.lfs.2015.04.003

Begutachteter Zeitschriftenartikel

Meister, M.; Tounsi, A.; Gaffal, E.; Bald, T.; Papatriantafyllou, M.; Ludwig, J.; Pougialis, G.; Bestvater, F.; Klotz, L.; Moldenhauer, G.; Tüting, T.; Hämmerling, G.J.; Arnold, B.; Oelert, T.

Self-Antigen Presentation by Keratinocytes in the Inflamed Adult Skin Modulates T-Cell Auto-Reactivity
In: Journal of Investigative Dermatology, Vol. 135, 2015, Issue 8, S. 1996-2004, 10.1038/jid.2015.130

Begutachteter Zeitschriftenartikel

Lu, K.-H.; Tounsi, A.; Shridhar, N.; Küblbeck, G.; Klevenz, A.; Prokosch, S.; Bald, T.; Tüting, T.; Arnold, B.

Dickkopf-3 contributes to the regulation of anti-tumor immune responses by mesenchymal stem cells
In: Frontiers in Immunology, Vol. 6, 2015, Issue DEC, 10.3389/fimmu.2015.00645

Begutachteter Zeitschriftenartikel

Riesenberg, S.; Groetchen, A.; Siddaway, R.; Bald, T.; Reinhardt, J.; Smorra, D.; Kohlmeyer, J.; Renn, M.; Phung, B.; Aymans, P.; Schmidt, T.; Hornung, V.; Davidson, I.; Goding, C.R.; Jönsson, G.; Landsberg, J.; Tüting, T.; Hölzel, M.

MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment
In: Nature Communications, Vol. 6, 2015, 10.1038/ncomms9755

2014

Begutachteter Zeitschriftenartikel

Schmitz, A.-L.; Schrage, R.; Gaffal, E.; Charpentier, T.H.; Wiest, J.; Hiltensperger, G.; Morschel, J.; Hennen, S.; Häußler, D.; Horn, V.; Wenzel, D.; Grundmann, M.; Büllesbach, K.M.; Schröder, R.; Brewitz, H.H.; Schmidt, J.; Gomeza, J.; Galés, C.; Fleischmann, B.K.; Tüting, T.; Imhof, D.; Tietze, D.; Gütschow, M.; Holzgrabe, U.; Sondek, J.; Harden, T.K.; Mohr, K.; Kostenis, E.

A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation
In: Chemistry and Biology, Vol. 21, 2014, Issue 7, S. 890-902, 10.1016/j.chembiol.2014.06.003

Begutachteter Zeitschriftenartikel

Sistigu, A.; Yamazaki, T.; Vacchelli, E.; Chaba, K.; Enot, D.P.; Adam, J.; Vitale, I.; Goubar, A.; Baracco, E.E.; Remédios, C.; Fend, L.; Hannani, D.; Aymeric, L.; Ma, Y.; Niso-Santano, M.; Kepp, O.; Schultze, J.L.; Tüting, T.; Belardelli, F.; Bracci, L.; La Sorsa, V.; Ziccheddu, G.; Sestili, P.; Urbani, F.; Delorenzi, M.; Lacroix-Triki, M.; Quidville, V.; Conforti, R.; Spano, J.-P.; Pusztai, L.; Poirier-Colame, V.; Delaloge, S.; Penault-Llorca, F.; Ladoire, S.; Arnould, L.; Cyrta, J.; Dessoliers, M.-C.; Eggermont, A.; Bianchi, M.E.; Pittet, M.; Engblom, C.; Pfirschke, C.; Préville, X.; Uzè, G.; Schreiber, R.D.; Chow, M.T.; Smyth, M.J.; Proietti, E.; André, F.; Kroemer, G.; Zitvogel, L.

Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy
In: Nature medicine, Vol. 20, 2014, Issue 11, S. 1301-1309, 10.1038/nm.3708

Begutachteter Zeitschriftenartikel

Gaffal, E.; Glodde, N.; Jakobs, M.; Bald, T.; Tüting, T.

Cannabinoid 1 receptors in keratinocytes attenuate fluorescein isothiocyanate-induced mouse atopic-like dermatitis
In: Experimental Dermatology, Vol. 23, 2014, Issue 6, S. 401-406, 10.1111/exd.12414

Begutachteter Zeitschriftenartikel

Gaffal, E.; Jakobs, M.; Glodde, N.; Schröder, R.; Kostenis, E.; Tüting, T.

β-arrestin 2 inhibits proinflammatory chemokine production and attenuates contact allergic inflammation in the skin
In: Journal of Investigative Dermatology, Vol. 134, 2014, Issue 8, S. 2131-2137, 10.1038/jid.2014.117

Begutachteter Zeitschriftenartikel

Bald, T.; Landsberg, J.; Lopez-Ramos, D.; Renn, M.; Glodde, N.; Jansen, P.; Gaffal, E.; Steitz, J.; Tolba, R.; Kalinke, U.; Limmer, A.; Jönsson, G.; Hölzel, M.; Tüting, T.

Immune cell-poor melanomas benefit from PD-1 blockade after targeted type I IFN activation
In: Cancer Discovery, Vol. 4, 2014, Issue 6, S. 674-687, 10.1158/2159-8290.CD-13-0458

Begutachteter Zeitschriftenartikel

Bald, T.; Quast, T.; Landsberg, J.; Rogava, M.; Glodde, N.; Lopez-Ramos, D.; Kohlmeyer, J.; Riesenberg, S.; Van Den Boorn-Konijnenberg, D.; Hömig-Hölzel, C.; Reuten, R.; Schadow, B.; Weighardt, H.; Wenzel, D.; Helfrich, I.; Schadendorf, D.; Bloch, W.; Bianchi, M.E.; Lugassy, C.; Barnhill, R.L.; Koch, M.; Fleischmann, B.K.; Förster, I.; Kastenmüller, W.; Kolanus, W.; Hölzel, M.; Gaffal, E.; Tüting, T.

Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma
In: Nature, Vol. 507, 2014, Issue 7490, S. 109-113, 10.1038/nature13111

2013

Begutachteter Zeitschriftenartikel

Gehrke, N.; Mertens, C.; Zillinger, T.; Wenzel, J.; Bald, T.; Zahn, S.; Tüting, T.; Hartmann, G.; Barchet, W.

Oxidative damage of dna confers resistance to cytosolic nuclease trex1 degradation and potentiates STING-dependent immune sensing
In: Immunity, Vol. 39, 2013, Issue 3, S. 482-495, 10.1016/j.immuni.2013.08.004

Begutachteter Zeitschriftenartikel

Gaffal, E.; Cron, M.; Glodde, N.; Tüting, T.

Anti-inflammatory activity of topical THC in DNFB-mediated mouse allergic contact dermatitis independent of CB1 and CB2 receptors
In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 68, 2013, Issue 8, S. 994-1000, 10.1111/all.12183

Begutachteter Zeitschriftenartikel

Tüting, T.

T cell immunotherapy for melanoma from bedside to bench to barn and back: How conceptual advances in experimental mouse models can be translated into clinical benefit for patients
In: Pigment Cell and Melanoma Research, Vol. 26, 2013, Issue 4, S. 441-456, 10.1111/pcmr.12111

Begutachteter Zeitschriftenartikel

Gaffal, E.; Cron, M.; Glodde, N.; Bald, T.; Kuner, R.; Zimmer, A.; Lutz, B.; Tüting, T.

Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation
In: Journal of Immunology, Vol. 190, 2013, Issue 10, S. 4929-4936, 10.4049/jimmunol.1201777

Begutachteter Zeitschriftenartikel

Hölzel, M.; Bovier, A.; Tüting, T.

Plasticity of tumour and immune cells: A source of heterogeneity and a cause for therapy resistance?
In: Nature Reviews Cancer, Vol. 13, 2013, Issue 5, S. 365-376, 10.1038/nrc3498

Begutachteter Zeitschriftenartikel

Steitz, J.; Tüting, T.

Biolistic DNA vaccination against melanoma
In: Methods in Molecular Biology, Vol. 940, 2013, S. 317-337, 10.1007/978-1-62703-110-3_24

Begutachteter Zeitschriftenartikel

Zahn, S.; Graef, M.; Barchet, W.; Bieber, T.; Tüting, T.; Wenzel, J.

Nitrosative stress: A hallmark of the junctional inflammation in cutaneous lupus erythematosus
In: Clinical and Experimental Dermatology, Vol. 38, 2013, Issue 1, S. 96-97, 10.1111/j.1365-2230.2012.04472.x

2012

Begutachteter Zeitschriftenartikel

Landsberg, J.; Kohlmeyer, J.; Renn, M.; Bald, T.; Rogava, M.; Cron, M.; Fatho, M.; Lennerz, V.; Wölfel, T.; Hölzel, M.; Tüting, T.

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation
In: Nature, Vol. 490, 2012, Issue 7420, S. 412-416, 10.1038/nature11538

Begutachteter Zeitschriftenartikel

Hornung, T.; Ko, A.; Tüting, T.; Bieber, T.; Wenzel, J.

Efficacy of low-dose methotrexate in the treatment of dermatomyositis skin lesions
In: Clinical and Experimental Dermatology, Vol. 37, 2012, Issue 2, S. 139-142, 10.1111/j.1365-2230.2011.04188.x

2011

Begutachteter Zeitschriftenartikel

Koch, P.; Breuer, P.; Peitz, M.; Jungverdorben, J.; Kesavan, J.; Poppe, D.; Doerr, J.; Ladewig, J.; Mertens, J.; Tüting, T.; Hoffmann, P.; Klockgether, T.; Evert, B.O.; Wüllner, U.; Brüstle, O.

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease
In: Nature, Vol. 480, 2011, Issue 7378, S. 543-546, 10.1038/nature10671

Begutachteter Zeitschriftenartikel

Freutel, S.; Gaffal, E.; Zahn, S.; Bieber, T.; Tüting, T.; Wenzel, J.

Enhanced CCR5+/CCR3+ T helper cell ratio in patients with active cutaneous lupus erythematosus
In: Lupus, Vol. 20, 2011, Issue 12, S. 1300-1304, 10.1177/0961203311409267

Begutachteter Zeitschriftenartikel

Kübler, K.; tho Pesch, C.; Gehrke, N.; Riemann, S.; Daßler, J.; Coch, C.; Landsberg, J.; Wimmenauer, V.; Pölcher, M.; Rudlowski, C.; Tüting, T.; Kuhn, W.; Hartmann, G.; Barchet, W.

Immunogenic cell death of human ovarian cancer cells induced by cytosolic poly(I:C) leads to myeloid cell maturation and activates NK cells
In: European Journal of Immunology, Vol. 41, 2011, Issue 10, S. 3028-3039, 10.1002/eji.201141555

Begutachteter Zeitschriftenartikel

Gaffal, E.; Gaffal, J.; Bald, T.; Sporleder, A.; Kohlmeyer, J.; Tüting, T.

Neonatal UVB exposure accelerates melanoma growth and enhances distant metastases in Hgf-Cdk4 R24C C57BL/6 mice
In: International Journal of Cancer, Vol. 129, 2011, Issue 2, S. 285-294, 10.1002/ijc.25913

Begutachteter Zeitschriftenartikel

Zahn, S.; Barchet, W.; Rehkämper, C.; Hornung, T.; Bieber, T.; Tüting, T.; Wenzel, J.

Enhanced skin expression of melanoma differentiation-associated gene 5 (MDA5) in dermatomyositis and related autoimmune diseases
In: Journal of the American Academy of Dermatology, Vol. 64, 2011, Issue 5, S. 988-989, 10.1016/j.jaad.2010.08.004

Begutachteter Zeitschriftenartikel

Zahn, S.; Rehkämper, C.; Kümmerer, B.M.; Ferring-Schmidt, S.; Bieber, T.; Tüting, T.; Wenzel, J.

Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFNλ) in cutaneous lupus erythematosus
In: Journal of Investigative Dermatology, Vol. 131, 2011, Issue 1, S. 133-140, 10.1038/jid.2010.244

2010

Begutachteter Zeitschriftenartikel

Landsberg, J.; Gaffal, E.; Cron, M.; Kohlmeyer, J.; Renn, M.; Tüting, T.

Autochthonous primary and metastatic melanomas in Hgf-Cdk4R24C mice evade T-cell-mediated immune surveillance
In: Pigment Cell and Melanoma Research, Vol. 23, 2010, Issue 5, S. 649-660, 10.1111/j.1755-148X.2010.00744.x

Begutachteter Zeitschriftenartikel

Osen, W.; Soltek, S.; Song, M.; Leuchs, B.; Steitz, J.; Tüting, T.T.; Eichmüller, S.B.E.; Nguyen, X.; Schadendorf, D.; Paschen, A.

Screening of human tumor antigens for CD4+ T cell epitopes by combination of HLA-transgenic mice, recombinant adenovirus and antigen peptide libraries
In: PLoS ONE, Vol. 5, 2010, Issue 11, 10.1371/journal.pone.0014137

Begutachteter Zeitschriftenartikel

Tüting, T.

Of swords and ploughshares: Immunosurveillance and inflammation in melanoma
In: Pigment Cell and Melanoma Research, Vol. 23, 2010, Issue 6, S. 727-728, 10.1111/j.1755-148X.2010.00754.x

Begutachteter Zeitschriftenartikel

Wenzel, J.; Zahn, S.; Tüting, T.

Pathogenesis of cutaneous lupus erythematosus: Common and different features in distinct subsets
In: Lupus, Vol. 19, 2010, Issue 9, S. 1020-1028, 10.1177/0961203310370046

Begutachteter Zeitschriftenartikel

Stabenow, D.; Frings, M.; Trück, C.; Gärtner, K.; Förster, I.; Kurts, C.; Tüting, T.; Odentha, M.; Dienes, H.-P.; Cederbrant, K.; Protzer, U.; Knolle, P.A.

Bioluminescence imaging allows measuring CD8 T cell function in the liver
In: Hepatology, Vol. 51, 2010, Issue 4, S. 1430-1437, 10.1002/hep.23575

Begutachteter Zeitschriftenartikel

Eberle, J.; Spangler, B.; Becker, J.C.; Heinemann, S.H.; Klein, C.A.; Kunz, M.; Kuphal, S.; Langer, P.; Mauch, C.; Meierjohann, S.; Paschen, A.; Schadendorf, D.; Schartl, M.; Schittek, B.; Schönherr, R.; Tüting, T.; Zigrino, P.; Bosserhoff, A.K.

Multicentre study on standardisation of melanoma cell culture - An initiative of the German Melanoma Research Network
In: Pigment Cell and Melanoma Research, Vol. 23, 2010, Issue 2, S. 296-298, 10.1111/j.1755-148X.2010.00684.x

Begutachteter Zeitschriftenartikel

Backer, R.; Schwandt, T.; Greuter, M.; Oosting, M.; Jüngerkes, F.; Tüting, T.; Boon, L.; O'Toole, T.; Kraal, G.; Limmer, A.; Den Haan, J.M.M.

Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, 2010, Issue 1, S. 216-221, 10.1073/pnas.0909541107

Begutachteter Zeitschriftenartikel

Petrosino, S.; Cristino, L.; Karsak, M.; Gaffal, E.; Ueda, N.; Tüting, T.; Bisogno, T.; De Filippis, D.; D'Amico, A.; Saturnino, C.; Orlando, P.; Zimmer, A.; Iuvone, T.; Di Marzo, V.

Protective role of palmitoylethanolamide in contact allergic dermatitis
In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 65, 2010, Issue 6, S. 698-711, 10.1111/j.1398-9995.2009.02254.x

Begutachteter Zeitschriftenartikel

Hendrickson, R.C.; Cicinnati, V.R.; Albers, A.; Dworacki, G.; Gambotto, A.; Pagliano, O.; Tüting, T.; Mayordomo, J.I.; Visus, C.; Appella, E.; Shabanowitz, J.; Hunt, D.F.; Deleo, A.B.

Identification of a 17β-hydroxysteroid dehydrogenase type 12 pseudogene as the source of a highly restricted BALB/c Meth A tumor rejection peptide
In: Cancer Immunology, Immunotherapy, Vol. 59, 2010, Issue 1, S. 113-124, 10.1007/s00262-009-0730-7

2009

Begutachteter Zeitschriftenartikel

Ney, J.T.; Schmidt, T.; Kurts, C.; Zhou, Q.; Eckert, D.; Felsher, D.W.; Schorle, H.; Knolle, P.; Tüting, T.; Barchet, W.; Büttner, R.; Limmer, A.; Gütgemann, I.

Autochthonous liver tumors induce systemic T cell tolerance associated with T cell receptor down-modulation
In: Hepatology, Vol. 49, 2009, Issue 2, S. 471-481, 10.1002/hep.22652

Begutachteter Zeitschriftenartikel

Cicinnati, V.R.; Kang, J.; Hou, J.; Lindemann, M.; Koop, K.; Tüting, T.; Gerken, G.; Beckebaum, S.

Interferon-α differentially affects homeostasis of human plasmacytoid and myeloid dendritic cells
In: Journal of Interferon and Cytokine Research, Vol. 29, 2009, Issue 3, S. 145-159, 10.1089/jir.2008.0011

Begutachteter Zeitschriftenartikel

Wenzel, J.; Zahn, S.; Bieber, T.; Tüting, T.

Type I interferon-associated cytotoxic inflammation in cutaneous lupus erythematosus
In: Archives of Dermatological Research, Vol. 301, 2009, Issue 1, S. 83-86, 10.1007/s00403-008-0892-8

Begutachteter Zeitschriftenartikel

Wiechert, A.; Reinhard, G.; Tüting, T.; Uerlich, M.; Bieber, T.; Wenzel, J.

Multiple skin cancers in a patient treated with hydroxyurea [Multiple kutane Neoplasien nach Therapie mit Hydroxyurea]
In: Hautarzt, Vol. 60, 2009, Issue 8, S. 651-654, 10.1007/s00105-008-1673-1

Begutachteter Zeitschriftenartikel

Kohlmeyer, J.; Cron, M.; Landsberg, J.; Bald, T.; Renn, M.; Mikus, S.; Bondong, S.; Wikasari, D.; Gaffal, E.; Hartmann, G.; Tüting, T.

Complete regression of advanced primary and metastatic mouse melanomas following combination chemoimmunotherapy
In: Cancer Research, Vol. 69, 2009, Issue 15, S. 6265-6274, 10.1158/0008-5472.CAN-09-0579

Begutachteter Zeitschriftenartikel

Tormo, D.; CheciÅ¿ska, A.; Alonso-Curbelo, D.; Pérez-Guijarro, E.; Cañón, E.; Riveiro-Falkenbach, E.; Calvo, T.G.; Larribere, L.; Megías, D.; Mulero, F.; Piris, M.A.; Dash, R.; Barral, P.M.; Rodríguez-Peralto, J.L.; Ortiz-Romero, P.; Tüting, T.; Fisher, P.B.; Soengas, M.S.

Targeted Activation of Innate Immunity for Therapeutic Induction of Autophagy and Apoptosis in Melanoma Cells
In: Cancer Cell, Vol. 16, 2009, Issue 2, S. 103-114, 10.1016/j.ccr.2009.07.004

2008

Buchbeitrag

Tüting, T.

New ways in melanoma therapy [Neue wege in der melanomtherapie]
In: JDDG - Journal of the German Society of Dermatology, Vol. 6, 2008, Issue 10, S. 815-816, 10.1111/j.1610-0387.2008.06879.x

Buchbeitrag

Wenzel, J.; Tüting, T.

An IFN-associated cytotoxic cellular immune response against viral, self-, or tumor antigens is a common pathogenetic feature in "interface dermatitis"
In: Journal of Investigative Dermatology, Vol. 128, 2008, Issue 10, S. 2392-2402, 10.1038/jid.2008.96

Begutachteter Zeitschriftenartikel

Betz, R.C.; König, K.; Flaquer, A.; Redler, S.; Eigelshoven, S.; Kortüm, A.-K.; Hanneken, S.; Hillmer, A.; Tüting, T.; Lambert, J.; De Weert, J.; Kruse, R.; Lutz, G.; Blaumeiser, B.; Nöthen, M.M.

The R620W polymorphism in PTPN22 confers general susceptibility for the development of alopecia areata
In: British Journal of Dermatology, Vol. 158, 2008, Issue 2, S. 389-391, 10.1111/j.1365-2133.2007.08312.x

Begutachteter Zeitschriftenartikel

Wenzel, J.; Peters, B.; Zahn, S.; Birth, M.; Hofmann, K.; Küsters, D.; Tomiuk, S.; Baron, J.M.; Merk, H.F.; Mauch, C.; Krieg, T.; Bieber, T.; Tüting, T.; Bosio, A.

Gene expression profiling of lichen planus reflects CXCL9+-mediated inflammation and distinguishes this disease from atopic dermatitis and psoriasis
In: Journal of Investigative Dermatology, Vol. 128, 2008, Issue 1, S. 67-78, 10.1038/sj.jid.5700945

Begutachteter Zeitschriftenartikel

Booken, N.; Gratchev, A.; Utikal, J.; Weiß, C.; Yu, X.; Qadoumi, M.; Schmuth, M.; Sepp, N.; Nashan, D.; Rass, K.; Tüting, T.; Assaf, C.; Dippel, E.; Stadler, R.; Klemke, C.-D.; Goerdt, S.

Sézary syndrome is a unique cutaneous T-cell lymphoma as identified by an expanded gene signature including diagnostic marker molecules CDO1 and DNM3
In: Leukemia, Vol. 22, 2008, Issue 2, S. 393-399, 10.1038/sj.leu.2405044

Begutachteter Zeitschriftenartikel

Wenzel, J.; Tormo, D.; Tüting, T.

Toll-like receptor-agonists in the treatment of skin cancer: History, current developments and future prospects
In: Handbook of Experimental Pharmacology, Vol. 183, 2008, S. 201-220, 10.1007/978-3-540-72167-3-10

Begutachteter Zeitschriftenartikel

Wenzel, J.; Tomiuk, S.; Zahn, S.; Küsters, D.; Vahsen, A.; Wiechert, A.; Mikus, S.; Birth, M.; Scheler, M.; Von Bubnoff, D.; Baron, J.M.; Merk, H.F.; Mauch, C.; Krieg, T.; Bieber, T.; Bosio, A.; Hofmann, K.; Tüting, T.; Peters, B.

Transcriptional profiling identifies an interferon-associated host immune response in invasive squamous cell carcinoma of the skin
In: International Journal of Cancer, Vol. 123, 2008, Issue 11, S. 2605-2615, 10.1002/ijc.23799

Begutachteter Zeitschriftenartikel

Poeck, H.; Besch, R.; Maihoefer, C.; Renn, M.; Tormo, D.; Morskaya, S.S.; Kirschnek, S.; Gaffal, E.; Landsberg, J.; Hellmuth, J.; Schmidt, A.; Anz, D.; Bscheider, M.; Schwerd, T.; Berking, C.; Bourquin, C.; Kalinke, U.; Kremmer, E.; Kato, H.; Akira, S.; Meyers, R.; Häcker, G.; Neuenhahn, M.; Busch, D.; Ruland, J.; Rothenfusser, S.; Prinz, M.; Hornung, V.; Endres, S.; Tüting, T.; Hartmann, G.

5′-triphosphate-siRNA: Turning gene silencing and Rig-I activation against melanoma
In: Nature Medicine, Vol. 14, 2008, Issue 11, S. 1256-1263, 10.1038/nm.1887

Begutachteter Zeitschriftenartikel

Singh, B.; Ezziddin, S.; Palmedo, H.; Reinhardt, M.; Strunk, H.; Tüting, T.; Biersack, H.-J.; Ahmadzadehfar, H.

Preoperative 18F-FDG-PET/CT imaging and sentinel node biopsy in the detection of regional lymph node metastases in malignant melanoma
In: Melanoma Research, Vol. 18, 2008, Issue 5, S. 346-352, 10.1097/CMR.0b013e32830b363b

Begutachteter Zeitschriftenartikel

Wiechert, A.; Tüting, T.; Bieber, T.; Haidl, G.; Wenzel, J.

Subacute cutaneous lupus erythematosus in a leuprorelin-treated patient with prostate carcinoma
In: British Journal of Dermatology, Vol. 159, 2008, Issue 1, S. 231-233, 10.1111/j.1365-2133.2008.08587.x

Begutachteter Zeitschriftenartikel

Hamprecht, A.; Tüting, T.; Bieber, T.; Wenzel, J.

Successful treatment of recalcitrant malar rash in a patient with cutaneous lupus erythematosus with efalizumab
In: Clinical and Experimental Dermatology, Vol. 33, 2008, Issue 3, S. 347-348, 10.1111/j.1365-2230.2007.02648.x

Begutachteter Zeitschriftenartikel

Wenzel, J.; Lucas, S.; Zahn, S.; Mikus, S.; Metze, D.; Ständer, S.; von Stebut, E.; Hillen, U.; Bieber, T.; Tüting, T.

CXCR3 <-> ligand-mediated skin inflammation in cutaneous lichenoid graft-versus-host disease
In: Journal of the American Academy of Dermatology, Vol. 58, 2008, Issue 3, S. 437-442, 10.1016/j.jaad.2007.10.647

2007

Buchbeitrag

Tüting, T.

Preclinical development of melanoma vaccines with toll-like receptor ligands in a novel genetic mouse model
In: Arzneimittel-Forschung/Drug Research, Vol. 57, 2007, Issue 1, S. 67

Begutachteter Zeitschriftenartikel

Gaffal, E.; Schweichel, D.; Tormo, D.; Steitz, J.; Lenz, J.; Basner-Tschakarjan, E.; Limmer, A.; Tüting, T.

Comparative evaluation of CD8+CTL responses following gene gun immunization targeting the skin with intracutaneous injection of antigen-transduced dendritic cells
In: European Journal of Cell Biology, Vol. 86, 2007, Issue 11-12, S. 817-826, 10.1016/j.ejcb.2006.07.002

Begutachteter Zeitschriftenartikel

Scheler, M.; Wenzel, J.; Tüting, T.; Takikawa, O.; Bieber, T.; Von Bubnoff, D.

Indoleamine 2,3-dioxygenase (IDO): The antagonist of type I interferon-driven skin inflammation?
In: American Journal of Pathology, Vol. 171, 2007, Issue 6, S. 1936-1943, 10.2353/ajpath.2007.070281

Begutachteter Zeitschriftenartikel

Betz, R.C.; Pforr, J.; Flaquer, A.; Redler, S.; Hanneken, S.; Eigelshoven, S.; Kortüm, A.-K.; Tüting, T.; Lambert, J.; De Weert, J.; Hillmer, A.M.; Schmael, C.; Wienker, T.F.; Kruse, R.; Lutz, G.; Blaumeiser, B.; Nöthen, M.M.

Loss-of-function mutations in the filaggrin gene and alopecia areata: Strong risk factor for a severe course of disease in patients comorbid for atopic disease
In: Journal of Investigative Dermatology, Vol. 127, 2007, Issue 11, S. 2539-2543, 10.1038/sj.jid.5700915

Begutachteter Zeitschriftenartikel

SokoÅ¿owska-WojdyÅ¿o, M.; Speuser, P.; Tüting, T.

The neoplastic T cells' culture in cutaneous T cell lymphomas - Never ending challenge [Hodowla nowotworowych komórek T w chÅ¿oniakach pierwotnie skórnych z komórek T - Nieustaja̧ce wyzwanie]
In: Przeglad Dermatologiczny, Vol. 94, 2007, Issue 4, S. 495-499

Begutachteter Zeitschriftenartikel

Distelmaier, M.; Gaffal, E.; Wenzel, J.; Rabini, S.; Tüting, T.

Application study Bepanthol Body Lotion Plus for atopic skin [Anwendungsbeobachtung Bepanthol Körperlotion Plus bei atopischer Haut]
In: Kosmetische Medizin, Vol. 28, 2007, Issue 4, S. 182-185

Begutachteter Zeitschriftenartikel

Wenzel, J.; Zahn, S.; Mikus, S.; Wiechert, A.; Bieber, T.; Tüting, T.

The expression pattern of interferon-inducible proteins reflects the characteristic histological distribution of infiltrating immune cells in different cutaneous lupus erythematosus subsets
In: British Journal of Dermatology, Vol. 157, 2007, Issue 4, S. 752-757, 10.1111/j.1365-2133.2007.08137.x

Begutachteter Zeitschriftenartikel

Karsak, M.; Gaffal, E.; Date, R.; Wang-Eckhardt, L.; Rehnelt, J.; Petrosino, S.; Starowicz, K.; Steuder, R.; Schlicker, E.; Cravatt, B.; Mechoulam, R.; Buettner, R.; Werner, S.; Di Marzo, V.; Tüting, T.; Zimmer, A.

Attenuation of allergic contact dermatitis through the endocannabinoid system
In: Science, Vol. 316, 2007, Issue 5830, S. 1494-1497, 10.1126/science.1142265

Begutachteter Zeitschriftenartikel

Ten Freyhaus, K.; Kaiser, H.-W.; Proelss, J.; Tüting, T.; Bieber, T.; Wenzel, J.

Successful treatment of bullous congenital ichthyosiform erythroderma with erythromycin [2]
In: Dermatology, Vol. 215, 2007, Issue 1, S. 81-83, 10.1159/000102043

Begutachteter Zeitschriftenartikel

Wenzel, J.; Tüting, T.

Identification of type I interferon-associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches
In: Experimental Dermatology, Vol. 16, 2007, Issue 5, S. 454-463, 10.1111/j.1600-0625.2007.00556.x

Begutachteter Zeitschriftenartikel

Wenzel, J.; Wiechert, A.; Merkel, C.; Bieber, T.; Tüting, T.

IP10/CXCL10 - CXCR3 interaction: A potential self-recruiting mechanism for cytotoxic lymphocytes in lichen sclerosus et atrophicus
In: Acta Dermato-Venereologica, Vol. 87, 2007, Issue 2, S. 112-117, 10.2340/00015555-0194

Begutachteter Zeitschriftenartikel

Wenzel, J.; Proelss, J.; Wiechert, A.; Zahn, S.; Bieber, T.; Tüting, T.

CXCR3-mediated recruitment of cytotoxic lymphocytes in lupus erythematosus profundus
In: Journal of the American Academy of Dermatology, Vol. 56, 2007, Issue 4, S. 648-650, 10.1016/j.jaad.2006.08.014

2006

Begutachteter Zeitschriftenartikel

Tormo, D.; Ferrer, A.; Gaffal, E.; Wenzel, J.; Basner-Tschakarjan, E.; Steitz, J.; Heukamp, L.C.; Gütgemann, I.; Buettner, R.; Malumbres, M.; Barbacid, M.; Merlino, G.; Tüting, T.

Rapid growth of invasive metastatic melanoma in carcinogen-treated hepatocyte growth factor/scatter factor-transgenic mice carrying an oncogenic CDK4 mutation
In: American Journal of Pathology, Vol. 169, 2006, Issue 2, S. 665-672, 10.2353/ajpath.2006.060017

Begutachteter Zeitschriftenartikel

Wingender, G.; Garbi, N.; Schumak, B.; Jüngerkes, F.; Endl, E.; von Bubnoff, D.; Steitz, J.; Striegler, J.; Moldenhauer, G.; Tüting, T.; Heit, A.; Huster, K.M.; Takikawa, O.; Akira, S.; Busch, D.H.; Wagner, H.; Hämmerling, G.J.; Knolle, P.A.; Limmer, A.

Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO
In: European Journal of Immunology, Vol. 36, 2006, Issue 1, S. 12-20, 10.1002/eji.200535602

Begutachteter Zeitschriftenartikel

Steitz, J.; Büchs, S.; Tormo, D.; Ferrer, A.; Wenzel, J.; Huber, C.; Wölfel, T.; Barbacid, M.; Malumbres, M.; Tüting, T.

Evaluation of genetic melanoma vaccines in cdk4-mutant mice provides evidence for immunological tolerance against autochthonous melanomas in the skin
In: International Journal of Cancer, Vol. 118, 2006, Issue 2, S. 373-380, 10.1002/ijc.21349

Begutachteter Zeitschriftenartikel

Chromik, J.; Schnürer, E.; Georg Meyer, R.; Wehler, T.; Tüting, T.; Wölfel, T.; Huber, C.; Herr, W.

Proteasome-inhibited dendritic cells demonstrate improved presentation of exogenous synthetic and natural HLA-class I peptide epitopes
In: Journal of Immunological Methods, Vol. 308, 2006, Issue 1-2, S. 77-89, 10.1016/j.jim.2005.09.021

Begutachteter Zeitschriftenartikel

Reinhardt, M.J.; Joe, A.Y.; Jaeger, U.; Huber, A.; Matthies, A.; Bucerius, J.; Roedel, R.; Strunk, H.; Bieber, T.; Biersack, H.-J.; Tüting, T.

Diagnostic performance of whole body dual modality 18F-FDG PET/CT imaging for N- and M-staging of malignant melanoma: Experience with 250 consecutive patients
In: Journal of Clinical Oncology, Vol. 24, 2006, Issue 7, S. 1178-1187, 10.1200/JCO.2005.03.5634

Begutachteter Zeitschriftenartikel

Steitz, J.; Britten, C.M.; Wölfel, T.; Tüting, T.

Effective induction of anti-melanoma immunity following genetic vaccination with synthetic mRNA coding for the fusion protein EGFP.TRP2
In: Cancer Immunology, Immunotherapy, Vol. 55, 2006, Issue 3, S. 246-253, 10.1007/s00262-005-0042-5

Begutachteter Zeitschriftenartikel

Steitz, J.; Tormo, D.; Schweichel, D.; Tüting, T.

Comparison of recombinant adenovirus and synthetic peptide for DC-based melanoma vaccination
In: Cancer Gene Therapy, Vol. 13, 2006, Issue 3, S. 318-325, 10.1038/sj.cgt.7700894

Begutachteter Zeitschriftenartikel

Tormo, D.; Ferrer, A.; Bosch, P.; Gaffal, E.; Basner-Tschakarjan, E.; Wenzel, J.; Tüting, T.

Therapeutic efficacy of antigen-specific vaccination and toll-like receptor stimulation against established transplanted and autochthonous melanoma in mice
In: Cancer Research, Vol. 66, 2006, Issue 10, S. 5427-5435, 10.1158/0008-5472.CAN-06-0399

Begutachteter Zeitschriftenartikel

Wenzel, J.; Schmidt, R.; Proelss, J.; Zahn, S.; Bieber, T.; Tüting, T.

Type I interferon-associated skin recruitment of CXCR3+ lymphocytes in dermatomyositis
In: Clinical and Experimental Dermatology, Vol. 31, 2006, Issue 4, S. 576-582, 10.1111/j.1365-2230.2006.02150.x

Begutachteter Zeitschriftenartikel

Utikal, J.; Poenitz, N.; Gratchev, A.; Klemke, C.-D.; Nashan, D.; Tüting, T.; Goerdt, S.

Additional Her 2/neu gene copies in patients with Sézary syndrome
In: Leukemia Research, Vol. 30, 2006, Issue 6, S. 755-760, 10.1016/j.leukres.2005.10.012

Begutachteter Zeitschriftenartikel

Huber, A.; Gaffal, E.; Bieber, T.; Tüting, T.; Wenzel, J.

Treatment of recalcitrant dermatomyositis with efalizumab [3]
In: Acta Dermato-Venereologica, Vol. 86, 2006, Issue 3, S. 254-255, 10.2340/00015555-0058

Begutachteter Zeitschriftenartikel

Schweichel, D.; Steitz, J.; Tormo, D.; Gaffal, E.; Ferrer, A.; Büchs, S.; Speuser, P.; Limmer, A.; Tüting, T.

Evaluation of DNA vaccination with recombinant adenoviruses using bioluminescence imaging of antigen expression: Impact of application routes and delivery with dendritic cells
In: Journal of Gene Medicine, Vol. 8, 2006, Issue 10, S. 1243-1250, 10.1002/jgm.952

Begutachteter Zeitschriftenartikel

Wenzel, J.; Scheler, M.; Proelss, J.; Bieber, T.; Tüting, T.

Type I interferon-associated cytotoxic inflammation in lichen planus
In: Journal of Cutaneous Pathology, Vol. 33, 2006, Issue 10, S. 672-678, 10.1111/j.1600-0560.2006.00527.x

Begutachteter Zeitschriftenartikel

Huber, A.; Tüting, T.; Bauer, R.; Bieber, T.; Wenzel, J.

Methotrexate treatment in cutaneous lupus erythematosus: Subcutaneous application is as effective as intravenous administration [16]
In: British Journal of Dermatology, Vol. 155, 2006, Issue 4, S. 861-862, 10.1111/j.1365-2133.2006.07431.x

Begutachteter Zeitschriftenartikel

Basner-Tschakarjan, E.; Gaffal, E.; O'Keeffe, M.; Tormo, D.; Limmer, A.; Wagner, H.; Hochrein, H.; Tüting, T.

Adenovirus efficiently transduces plasmacytoid dendritic cells resulting in TLR9-dependent maturation and IFN-α production
In: Journal of Gene Medicine, Vol. 8, 2006, Issue 11, S. 1300-1306, 10.1002/jgm.964

2005

Begutachteter Zeitschriftenartikel

Wenzel, J.; Uerlich, M.; Wörrenkämper, E.; Freutel, S.; Bieber, T.; Tüting, T.

Scarring skin lesions of discoid lupus erythematosus are characterized by high numbers of skin-homing cytotoxic lymphocytes associated with strong expression of the type I interferon-induced protein MxA
In: British Journal of Dermatology, Vol. 153, 2005, Issue 5, S. 1011-1015, 10.1111/j.1365-2133.2005.06784.x

Begutachteter Zeitschriftenartikel

Sokolowska-Wojdylo, M.; Wenzel, J.; Gaffal, E.; Steitz, J.; Roszkiewicz, J.; Bieber, T.; Tüting, T.

Absence of CD26 expression on skin-homing CLA+ CD4+ T lymphocytes in peripheral blood is a highly sensitive marker for early diagnosis and therapeutic monitoring of patients with Sézary syndrome
In: Clinical and Experimental Dermatology, Vol. 30, 2005, Issue 6, S. 702-706, 10.1111/j.1365-2230.2005.01904.x

Begutachteter Zeitschriftenartikel

Wenzel, J.; Gütgemann, I.; Distelmaier, M.; Uerlich, M.; Mikus, S.; Bieber, T.; Tüting, T.

The role of cytotoxic skin-homing CD8+ lymphocytes in cutaneous cytotoxic T-cell lymphoma and pityriasis lichenoides
In: Journal of the American Academy of Dermatology, Vol. 53, 2005, Issue 3, S. 422-427, 10.1016/j.jaad.2005.05.042

Begutachteter Zeitschriftenartikel

Wenzel, J.; Scheler, M.; Bieber, T.; Tüting, T.; Caproni, M.; Torchia, D.; Fabbri, P.

Evidence for a role of type I interferons in the pathogenesis of dermatomyositis [15] (multiple letters)
In: British Journal of Dermatology, Vol. 153, 2005, Issue 2, S. 462-464, 10.1111/j.1365-2133.2005.06786.x

Begutachteter Zeitschriftenartikel

Wenzel, J.; Brähler, S.; Bauer, R.; Bieber, T.; Tüting, T.

Efficacy and safety of methotrexate in recalcitrant cutaneous lupus erythematosus: Results of a retrospective study in 43 patients
In: British Journal of Dermatology, Vol. 153, 2005, Issue 1, S. 157-162, 10.1111/j.1365-2133.2005.06552.x

Begutachteter Zeitschriftenartikel

Wenzel, J.; Bekisch, B.; Uerlich, M.; Haller, O.; Bieber, T.; Tüting, T.

Type I interferon-associated recruitment of cytotoxic lymphocytes: A common mechanism in regressive melanocytic lesions
In: American Journal of Clinical Pathology, Vol. 124, 2005, Issue 1, S. 37-48, 10.1309/4EJ9-KL7C-GDEN-VVLE

Begutachteter Zeitschriftenartikel

Wenzel, J.; Henze, S.; Brähler, S.; Bieber, T.; Tüting, T.

The expression of human leukocyte antigen-DR and CD25 on circulating T cells in cutaneous lupus erythematosus and correlation with disease activity
In: Experimental Dermatology, Vol. 14, 2005, Issue 6, S. 454-459, 10.1111/j.0906-6705.2005.00301.x

Begutachteter Zeitschriftenartikel

Wenzel, J.; Henze, S.; Wörenkämper, E.; Basner-Tschakarjan, E.; Sokolowska-Wojdylo, M.; Steitz, J.; Bieber, T.; Tüting, T.

Role of the chemokine receptor CCR4 and its ligand thymus- and activation-regulated chemokine/CCL17 for lymphocyte recruitment in cutaneous lupus erythematosus
In: Journal of Investigative Dermatology, Vol. 124, 2005, Issue 6, S. 1241-1248, 10.1111/j.0022-202X.2005.23755.x

Begutachteter Zeitschriftenartikel

Brück, J.; Steitz, J.; Strand, D.; Tüting, T.

Altered intracellular sorting signals do not influence the efficacy of genetic melanoma vaccines incorporating helper determinants in mice
In: Journal of Gene Medicine, Vol. 7, 2005, Issue 5, S. 613-620, 10.1002/jgm.702

Begutachteter Zeitschriftenartikel

Steitz, J.; Bruck, J.; Lenz, J.; Buchs, S.; Tüting, T.

Erratum: Breaking tolerance - Another piece added to the vitiligo puzzle (Journal of Investigative Dermatology (2005) 124 (xiii-xv))
In: Journal of Investigative Dermatology, Vol. 124, 2005, Issue 5, S. 1092, 10.1111/j.0022-202X.2005.23751.x

Begutachteter Zeitschriftenartikel

Wenzel, J.; Bauer, R.; Bieber, T.; Tüting, T.

Successful rituximab treatment of severe Pemphigus vulgaris resistant to multiple immunosuppressants [8]
In: Acta Dermato-Venereologica, Vol. 85, 2005, Issue 2, S. 185-186, 10.1080/00015550410024111

Begutachteter Zeitschriftenartikel

Wenzel, J.; Philipp-Dormston, W.; Bieber, T.; Tüting, T.

Topical treatment of bullous pemphigoid with tacrolimus. Case report with brief literature review [Topische therapie des bullösen pemphigoids mit tacrolimus. Ein fallbericht mit kurzer übersicht die literatur]
In: JDDG - Journal of the German Society of Dermatology, Vol. 3, 2005, Issue 3, S. 207-210

Begutachteter Zeitschriftenartikel

Cicinnati, V.R.; Dworacki, G.; Albers, A.; Beckebaum, S.; Tüting, T.; Kaczmarek, E.; DeLeo, A.B.

Impact of p53-based immunization on primary chemically-induced tumors
In: International Journal of Cancer, Vol. 113, 2005, Issue 6, S. 961-970, 10.1002/ijc.20686

Begutachteter Zeitschriftenartikel

Wenzel, J.; Wörenkämper, E.; Freutel, S.; Henze, S.; Haller, O.; Bieber, T.; Tüting, T.

Enhanced type I interferon signalling promotes Th1-biased inflammation in cutaneous lupus erythematosus
In: Journal of Pathology, Vol. 205, 2005, Issue 4, S. 435-442, 10.1002/path.1721

Begutachteter Zeitschriftenartikel

Sokolowska-Wojdylo, M.; Wenzel, J.; Gaffal, E.; Lenz, J.; Speuser, P.; Erdmann, S.; Abuzahra, F.; Bowman, E.; Roszkiewicz, J.; Bieber, T.; Tüting, T.

Circulating clonal CLA+ and CD4+ T cells in Sézary syndrome express the skin-homing chemokine receptors CCR4 and CCR10 as well as the lymph node-homing chemokine receptor CCR7
In: British Journal of Dermatology, Vol. 152, 2005, Issue 2, S. 258-264, 10.1111/j.1365-2133.2004.06325.x

Begutachteter Zeitschriftenartikel

Steitz, J.; Brück, J.; Lenz, J.; Büchs, S.; Tüting, T.

Peripheral CD8+ T cell tolerance against melanocytic self-antigens in the skin is regulated in two steps by CD4+ T cells and local inflammation: Implications for the pathophysiology of vitiligo
In: Journal of Investigative Dermatology, Vol. 124, 2005, Issue 1, S. 144-150, 10.1111/j.0022-202X.2004.23538.x

2004

Begutachteter Zeitschriftenartikel

De Palma, R.; Marigo, I.; Del Galdo, F.; De Santo, C.; Serafini, P.; Cingarlini, S.; Tüting, T.; Lenz, J.; Basso, G.; Milan, G.; Zanovello, P.; Bronte, V.

Therapeutic effectiveness of recombinant cancer vaccines is associated with a prevalent T-cell receptor α usage by melanoma-specific CD8+ T lymphocytes
In: Cancer Research, Vol. 64, 2004, Issue 21, S. 8068-8076, 10.1158/0008-5472.CAN-04-0067

Begutachteter Zeitschriftenartikel

Wenzel, J.; Montag, S.; Wilsmann-Theis, D.; Gaffal, E.; Bieber, T.; Tüting, T.

Successful treatment of recalcitrant Wegener's granulomatosis of the skin with tacrolimus (Prograf™) [1]
In: British Journal of Dermatology, Vol. 151, 2004, Issue 4, S. 927-928, 10.1111/j.1365-2133.2004.06187.x

Begutachteter Zeitschriftenartikel

Tuettenberg, A.; Jonuleit, H.; Tüting, T.; Brück, J.; Biermann, V.; Kochanek, S.; Knop, J.; Enk, A.H.

Early Adenoviral Gene Expression Mediates Immunosuppression by Transduced Dendritic Cell (DC): Implications for Immunotherapy Using Genetically Modified DC
In: Journal of Immunology, Vol. 172, 2004, Issue 3, S. 1524-1530

Begutachteter Zeitschriftenartikel

Steitz, J.; Wenzel, J.; Gaffal, E.; Tüting, T.

Initiation and regulation of CD8+T cells recognizing melanocytic antigens in the epidermis: Implications for the pathophysiology of vitiligo
In: European Journal of Cell Biology, Vol. 83, 2004, Issue 11-12, S. 797-803, 10.1078/0171-9335-00423

2003

Begutachteter Zeitschriftenartikel

Wenzel, J.; Bieber, T.; Uerlich, M.; Tüting, T.

Systemic treatment of cutaneous lupus erythematosus [Systemische therapie des kutanen lupus erythematodes]
In: JDDG - Journal of the German Society of Dermatology, Vol. 1, 2003, Issue 9, S. 694-704, 10.1046/j.1610-0387.2003.03024.x

Begutachteter Zeitschriftenartikel

Wenzel, J.; Tüting, T.; Bieber, T.

Cutaneous lesions in lupus erythematosus [Kutane manifestationen des lupus erythematodes]
In: Deutsche Medizinische Wochenschrift, Vol. 128, 2003, Issue 31-32, S. 1655-1658, 10.1055/s-2003-41095

Begutachteter Zeitschriftenartikel

Ross, R.; Sudowe, S.; Beisner, J.; Ross, X.-L.; Ludwig-Portugall, I.; Steitz, J.; Tüting, T.; Knop, J.; Reske-Kunz, A.B.

Transcriptional targeting of dendritic cells for gene therapy using the promoter of the cytoskeletal protein fascin
In: Gene Therapy, Vol. 10, 2003, Issue 12, S. 1035-1040, 10.1038/sj.gt.3301968

Begutachteter Zeitschriftenartikel

Tuettenberg, A.; Jonuleit, H.; Tüting, T.; Brück, J.; Knop, J.; Enk, A.H.

Priming of T cells with Ad-transduced DC followed by expansion with peptide-pulsed DC significantly enhances the induction of tumor-specific CD8+ T cells: Implications for an efficient vaccination strategy
In: Gene Therapy, Vol. 10, 2003, Issue 3, S. 243-250, 10.1038/sj.gt.3301880

2002

Begutachteter Zeitschriftenartikel

Müller, G.; Müller, A.; Tüting, T.; Steinbrink, K.; Saloga, J.; Szalma, C.; Knop, J.; Enk, A.H.

Interleukin-10-treated dendritic cells modulate immune responses of naive and sensitized T cells In vivo
In: Journal of Investigative Dermatology, Vol. 119, 2002, Issue 4, S. 836-841, 10.1046/j.1523-1747.2002.00496.x

Begutachteter Zeitschriftenartikel

Tüting, T.; Reinhard, G.

Tumor immunity and autoimmunity: Lessons for the development of modern melanome vaccines learned in murine models [Tumorimmunabwehr und autoimmunität: Erkenntnisse für die entwicklung moderner melanomvakzinen aus tierexperimentellen studien]
In: H+G Zeitschrift fur Hautkrankheiten, Vol. 77, 2002, Issue 11, S. 553-558, 10.1046/j.1439-0353.2002.02604.x

Begutachteter Zeitschriftenartikel

Steitz, J.; Brück, J.; Gambotto, A.; Knop, J.; Tüting, T.

Genetic immunization with a melanocytic self-antigen linked to foreign helper sequences breaks tolerance and induces autoimmunity and tumor immunity
In: Gene Therapy, Vol. 9, 2002, Issue 3, S. 208-213, 10.1038/sj/gt/3301634

Begutachteter Zeitschriftenartikel

Sudowe, S.; Montermann, E.; Steitz, J.; Tüting, T.; Knop, J.; Reske-Kunz, A.B.

Efficacy of recombinant adenovirus as vector for allergen gene therapy in a mouse model of type I allergy
In: Gene Therapy, Vol. 9, 2002, Issue 2, S. 147-156, 10.1038/sj/gt/3301625

2001

Begutachteter Zeitschriftenartikel

Steitz, J.; Brück, J.; Knop, J.; Tüting, T.

Adenovirus-transduced dendritic cells stimulate cellular immunity to melanoma via a CD4+ T cell-dependent mechanism
In: Gene Therapy, Vol. 8, 2001, Issue 16, S. 1255-1263, 10.1038/sj.gt.3301521

Begutachteter Zeitschriftenartikel

Jonuleit, H.; Giesecke-Tuettenberg, A.; Tüting, T.; Thurner-Schuler, B.; Stuge, T.B.; Paragnik, L.; Kandemir, A.; Lee, P.P.; Schuler, G.; Knop, J.; Enk, A.H.

A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection
In: International Journal of Cancer, Vol. 93, 2001, Issue 2, S. 243-251, 10.1002/ijc.1323

Begutachteter Zeitschriftenartikel

Steitz, J.; Brück, J.; Lenz, J.; Knop, J.; Tüting, T.

Depletion of CD25+ CD4+ T cells and treatment with tyrosinase-related protein 2-transduced dendritic cells enhance the interferon α-induced, CD8+ T-cell-dependent immune defense of B16 melanoma
In: Cancer Research, Vol. 61, 2001, Issue 24, S. 8643-8646

2000

Begutachteter Zeitschriftenartikel

Gambotto, A.; Dworacki, G.; Cicinnati, V.; Kenniston, T.; Steitz, J.; Tüting, T.; Robbins, P.D.; DeLeo, A.B.

Immunogenicity of enhanced green fluorescent protein (EGFP) in BALB/c mice: Identification of an H2-Kd-restricted CTL epitope
In: Gene Therapy, Vol. 7, 2000, Issue 23, S. 2036-2040, 10.1038/sj.gt.3301335

Begutachteter Zeitschriftenartikel

Steinbrink, K.; Paragnik, L.; Jonuleit, H.; Tüting, T.; Knop, J.; Enk, A.H.

Induction of dendritic cell maturation and modulation of dendritic cell-induced immune responses by prostaglandins
In: Archives of Dermatological Research, Vol. 292, 2000, Issue 9, S. 437-445

Begutachteter Zeitschriftenartikel

Steitz, J.; Brück, J.; Steinbrink, K.; Alexander, E.; Knop, J.; Tüting, T.

Genetic immunization of mice with human tyrosinase-related protein 2: Implications for the immunotherapy of melanoma
In: International Journal of Cancer, Vol. 86, 2000, Issue 1, S. 89-94, 10.1002/(SICI)1097-0215(20000401)86:1<89::AID-IJC14>3.0.CO;2-I

Begutachteter Zeitschriftenartikel

Jonuleit, H.; Tüting, T.; Steitz, J.; Brück, J.; Giesecke, A.; Steinbrink, K.; Knop, J.; Enk, A.H.

Efficient transduction of mature CD83+ dendritic cells using recombinant adenovirus suppressed T cell stimulatory capacity
In: Gene Therapy, Vol. 7, 2000, Issue 3, S. 249-254

Begutachteter Zeitschriftenartikel

Hiroishi, K.; Tüting, T.; Lotze, M.T.

IFN-α-expressing tumor cells enhance generation and promote survival of tumor-specific CTLs
In: Journal of Immunology, Vol. 164, 2000, Issue 2, S. 567-572

1999

Begutachteter Zeitschriftenartikel

Tüting, T.; Gambotto, A.; DeLeo, A.; Lotze, M.T.; Robbins, P.D.; Storkus, W.J.

Induction of tumor antigen-specific immunity using plasmid DNA immunization in mice
In: Cancer Gene Therapy, Vol. 6, 1999, Issue 1, S. 73-80

Begutachteter Zeitschriftenartikel

Hiroishi, K.; Tüting, T.; Tahara, H.; Lotze, M.T.

Interferon-alpha gene therapy in combination with CD80 transduction reduces tumorigenicity and growth of established tumor in poorly immunogenic tumor models
In: Gene Therapy, Vol. 6, 1999, Issue 12, S. 1988-1994, 10.1038/sj.gt.3301034

Begutachteter Zeitschriftenartikel

Gambotto, A.; Tüting, T.; McVey, D.L.; Kovesdi, I.; Tahara, H.; Lotze, M.T.; Robbins, P.D.

Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12
In: Cancer Gene Therapy, Vol. 6, 1999, Issue 1, S. 45-53

Begutachteter Zeitschriftenartikel

Tüting, T.; Steitz, J.; Brück, J.; Gambotto, A.; Steinbrink, K.; DeLeo, A.B.; Robbins, P.; Knop, J.; Enk, A.H.

Dendritic Cell-based Genetic Immunization in Mice with a Recombinant Adenovirus Encoding Murine TRP2 Induces Effective Anti-melanoma Immunity
In: Journal of Gene Medicine, Vol. 1, 1999, Issue 6, S. 400-406

Begutachteter Zeitschriftenartikel

Tüting, T.

The immunology of cutaneous DNA immunization
In: Current Opinion in Molecular Therapeutics, Vol. 1, 1999, Issue 2, S. 216-225

Begutachteter Zeitschriftenartikel

Tüting, T.; Gambotto, A.; Robbins, P.D.; Storkus, W.J.; DeLeo, A.B.

Co-delivery of T helper 1-biasing cytokine genes enhances the efficacy of gene gun immunization of mice: Studies with the model tumor antigen β-galactosidase and the BALB/c Meth A p53 tumor-specific antigen
In: Gene Therapy, Vol. 6, 1999, Issue 4, S. 629-636, 10.1038/sj.gt.3300859

1998

Begutachteter Zeitschriftenartikel

Tüting, T.; Storkus, W.J.; Falo Jr., L.D.

DNA immunization targeting the skin: Molecular control of adaptive immunity
In: Journal of Investigative Dermatology, Vol. 111, 1998, Issue 2, S. 183-188, 10.1046/j.1523-1747.1998.00261.x

Begutachteter Zeitschriftenartikel

Tüting, T.; Wilson, C.C.; Martin, D.M.; Kasamon, Y.L.; Rowles, J.; Ma, D.I.; Slingluff Jr., C.L.; Wagner, S.N.; Van Der Bruggen, P.; Baar, J.; Lotze, M.T.; Storkus, W.J.

Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro: Enhancement by cotransfection of genes encoding the Th1-biasing cytokines IL-12 and IFN-α
In: Journal of Immunology, Vol. 160, 1998, Issue 3, S. 1139-1147

Begutachteter Zeitschriftenartikel

Tüting, T.; Wilson, C.C.; Martin, D.M.; Baar, J.; DeLeo, A.; Lotze, M.T.; Storkus, W.J.

DNA vaccines targeting dendritic cells for the immunotherapy of cancer
In: Advances in Experimental Medicine and Biology, Vol. 451, 1998, S. 295-304

1997

Buchbeitrag

Tüting, T.; Zorina, T.; Ma, D.I.; Wilson, C.C.; De Cesare, C.M.; De Leo, A.B.; Lotze, M.T.; Storkus, W.J.

Development of dendritic cell-based genetic vaccines for cancer
In: Advances in Experimental Medicine and Biology, Vol. 417, 1997, S. 511-518

Begutachteter Zeitschriftenartikel

Tüting, T.; Gambotto, A.; Baar, J.; Davis, I.D.; Storkus, W.J.; Zavodny, P.J.; Narula, S.; Tahara, H.; Robbins, P.D.; Lotze, M.T.

Interferon-α gene therapy for cancer: Retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models
In: Gene Therapy, Vol. 4, 1997, Issue 10, S. 1053-1060

Begutachteter Zeitschriftenartikel

Tüting, T.; DeLeo, A.B.; Lotze, M.T.; Storkus, W.J.

Genetically modified bone marrow-derived dendritic cells expressing tumor-associated viral or 'self' antigens induce antitumor immunity in vivo
In: European Journal of Immunology, Vol. 27, 1997, Issue 10, S. 2702-2707, 10.1002/eji.1830271033

Begutachteter Zeitschriftenartikel

Tüting, T.; Storkus, W.J.; Lotze, M.T.

Gene-based strategies for the immunotherapy of cancer
In: Journal of Molecular Medicine, Vol. 75, 1997, Issue 7, S. 478-491, 10.1007/s001090050133

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